2 completed, 2 recruiting. 2 Phase 1, 2 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 2 | 2 | Recruiting 2 |
| Not applicable | 1 | Completed 1 |
Follow Werner Syndrome: new trials by email Literature Review of Werner Syndrome trials Research Report on Werner Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin in Werner Syndrome Progerinin - Werner Syndrome | Phase 2 | Recruiting | PRG Science & Technology Co., Ltd. | 5 | 2026-10-01 | 2026-10-05 |
| A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors. NDI-219216 - Advanced Solid Tumors Cancer, MSI-H Cancer | Phase 1 / Phase 2 | Recruiting | Nimbus Wadjet, Inc. | 134 | 2025-03-31 | 2026-05-06 |
| Phase I Study of Progerinin in Healthy Volunteers Progerinin, Placebo - Hutchinson-Gilford Progeria Syndrome, Werner Syndrome | Phase 1 | Completed | PRG Science & Technology Co., Ltd. | 64 | 2020-08-24 | 2021-09-22 |
| Descriptive Study of Recombinant Human Insulin-Like Growth Factor for Osteoporosis in Werner's Syndrome growth hormone - Werner's Syndrome | Not applicable | Completed | National Center for Research Resources (NCRR) | 1 | 1992-05-01 | 2005-06-24 |
Genetic Diseases, Inborn (1) · Microsatellite Instability (1) · Progeria (1) · Rare Diseases (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · DNA Repair-Deficiency Disorders (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Genetic Diseases, Inborn (3) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Disease Attributes (1) · Genomic Instability (1) · Laminopathies (1) · Metabolism, Inborn Errors (1)
Growth Hormone (1)
PRG Science & Technology Co., Ltd. (2) · National Center for Research Resources (NCRR) (1) · Nimbus Wadjet, Inc. (1)
United States (3) · Australia (1) · Canada (1) · France (1) · Ireland (1) · Portugal (1) · Spain (1) · United Kingdom (1)
Anita Scheuber, MD, PhD (1) · Craig D. Rubin (1)