3 recruiting, 1 completed. 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow VEXAS: new trials by email Literature Review of VEXAS trials Research Report on VEXAS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS) Pacritinib, Placebo - VEXAS, VEXAS Syndrome | Phase 2 | Recruiting | Swedish Orphan Biovitrum | 156 | 2025-05-28 | 2026-10-16 |
| Pacritinib in Vacuoles, E1 Ubiqutin-activating Enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) Syndrome Pacritinib - E1 Ubiqutin-activating Enzyme, X-linked, Autoinflammatory, Somatic Syndrome, VEXAS | Phase 1 | Recruiting | Washington University School of Medicine | 15 | 2025-02-13 | 2026-07-15 |
| HRQoL and Financial Toxicity in Patients With VEXAS Syndrome VEXAS | Recruiting | Gruppo Italiano Malattie EMatologiche dell'Adulto | 100 | 2024-11-01 | 2025-07-15 | |
| DECIPHERING AND TARGETING VEXAS VEXAS | Completed | IRCCS San Raffaele | 60 | 2021-01-01 | 2026-08-05 |
VEXAS syndrome (4) · Hematologic Neoplasms (1) · Inflammation (1) · Myelodysplastic Syndromes (1)
Bone Marrow Diseases (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Neoplasms (1) · Neoplasms by Site (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Gruppo Italiano Malattie EMatologiche dell'Adulto (1) · IRCCS San Raffaele (1) · Swedish Orphan Biovitrum (1) · Washington University School of Medicine (1)
Italy (3) · United States (2) · Canada (1) · France (1) · Germany (1) · Japan (1) · Spain (1) · United Kingdom (1)
Meagan A Jacoby, M.D., Ph.D. (1) · Simone Cenci, MD (1)