1 active not recruiting, 1 terminated. 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Active not recruiting 1, Terminated 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Unresectable Head and Neck Squamous Cell Carcinoma: new trials by email Literature Review of Unresectable Head and Neck Squamous Cell Carcinoma trials Research Report on Unresectable Head and Neck Squamous Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Combination Treatment of PDS0101 and Pembrolizumab, Pembrolizumab Monotherapy - Recurrent Head and Neck Cancer, Metastatic Head and Neck Cancer | Phase 3 | Terminated | PDS Biotechnology Corp. | 12 | 2025-05-30 | 2026-09-02 |
| A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 BNT113, Pembrolizumab - Unresectable Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Cancer | Phase 2 / Phase 3 | Active not recruiting | BioNTech SE | 358 | 2021-01-07 | 2026-10-28 |
Head and Neck Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Neoplasm Metastasis (1) · Neoplasms, Squamous Cell (1) · Recurrence (1)
Carcinoma (2) · Carcinoma, Squamous Cell (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Neoplasms, Glandular and Epithelial (2) · Disease Attributes (1) · Neoplastic Processes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
pembrolizumab (2)
BioNTech SE (1) · PDS Biotechnology Corp. (1)
United States (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · Canada (1) · Chile (1) · Czechia (1) · France (1) · Germany (1) · Hungary (1) · Israel (1) · Italy (1) · Mexico (1)