6 completed, 3 recruiting, 2 not yet recruiting, 2 terminated. 9 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 5, Recruiting 3, Not yet recruiting 1 |
| Phase 2 | 2 | Terminated 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Sperm DNA Fragmentation: new trials by email Literature Review of Sperm DNA Fragmentation trials Research Report on Sperm DNA Fragmentation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nordic Sperm DNA Study Lifestyle change - Male Infertility, Sperm DNA Fragmentation | Not applicable | Not yet recruiting | Regionshospitalet Viborg, Skive | 800 | 2026-09-01 | 2026-08-21 |
| Clinical Thresholds of Double-strand Breaks in Sperm's DNA in ART LensHooke X12 Device - Sperm DNA Fragmentation, Sperm DNA Impact on ART Outcomes | Not yet recruiting | Indira IVF Hospital Pvt Ltd | 484 | 2026-06-01 | 2026-06-05 | |
| Royal Jelly Supplementation in Unexplained Male Infertility Lyophilized Royal Jelly, Placebo - Unexplained Infertility, Male Infertility | Not applicable | Recruiting | Medipol University | 80 | 2026-02-01 | 2026-08-19 |
| Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development sperm separation device - DNA Damage, DNA Strand Breaks | Not applicable | Recruiting | Richard Kordus, PhD, HCLD (ABB) | 50 | 2025-08-11 | 2026-09-24 |
| HMG Treatment Reduces Sperm DNA Fragmentation Human Menopausal Gonadotropin (hMG), Vitamin E - Sperm DNA Fragmentation | Phase 1 | Completed | Jinling Hospital, China | 114 | 2025-07-02 | 2026-10-14 |
| The EPIC Study: Exploring Paternal Age and the Influence on Blastocyst Culture Microfluidic sperm separation device, Density grade centrifugation - Infertility (IVF Patients), Oocyte Competence | Not applicable | Recruiting | Reproductive Medicine Associates of New Jersey | 100 | 2025-04-09 | 2026-06-03 |
| Microfluidics Versus Density Gradient Centrifugation for Sperm Preparation in IVF Microfluidic sperm sorting, Density Gradient Centrifugation - Male Infertility, Sperm DNA Fragmentation | Not applicable | Completed | Hanoi Medical University | 119 | 2023-03-14 | 2025-06-05 |
| PGT-A Evaluates Advanced Sperm Selection in Embryos From High Teratozoospermia Males Sperm Selection - Teratozoospermia, Sperm DNA Fragmentation | Not applicable | Completed | Ganin Fertility Center | 264 | 2023-01-01 | 2024-01-30 |
| Impact of Telomere Biology and Sperm DNA Fragmentation on Embryonic Development Sperm DNA Fragmentation, Male Fertility | Unknown | IVI Madrid | 204 | 2022-08-22 | 2024-01-11 | |
| Advanced Sperm Selection Techniques and Their Contribution to Blastocyst Euploidy Rates PICSI, MACS - Sperm DNA Fragmentation, Infertility | Not applicable | Completed | Ganin Fertility Center | 515 | 2022-08-01 | 2024-05-07 |
| Effect of Different Sperm Processing Methods in ICSI Outcome. sperm processing method - Sperm DNA Fragmentation | Phase 2 / Phase 3 | Terminated | Benha University | 20 | 2018-05-01 | 2022-09-21 |
| Impact of Escitalopram on Sperm DNA Fragmentation Escitalopram, Placebo - Sperm DNA Fragmentation, Infertility, Male | Phase 2 | Terminated | Weill Medical College of Cornell University | 75 | 2017-10-01 | 2025-08-06 |
| Sperm Selection by Microfluidic Separation Improves Embryo Quality Microfluidic Sperm Sorting, in vitro fertilization - Sperm DNA Fragmentation, Embryo Quality | Not applicable | Completed | University of California, San Francisco | 393 | 2017-06-20 | 2025-12-31 |
| Sperm Selection by Either PICSI or MACS in Cases With Abnormal Sperm DNA Fragmentation Index for ICSI PICSI, MACS - Sperm DNA Fragmentation | Not applicable | Completed | Ganin Fertility Center | 396 | 2017-01-01 | 2020-07-21 |
Infertility, Male (5) · Infertility (4) · Teratozoospermia (1)
Genital Diseases (8) · Urogenital Diseases (8) · Genital Diseases, Male (6) · Male Urogenital Diseases (6) · Infertility (4) · Infertility, Male (1)
Centrifugation, Density Gradient (1) · Escitalopram (1) · Fertilization in Vitro (1) · Menotropins (1) · Vitamin E (1)
Ganin Fertility Center (3) · Benha University (1) · Hanoi Medical University (1) · IVI Madrid (1) · Indira IVF Hospital Pvt Ltd (1) · Jinling Hospital, China (1) · Medipol University (1) · Regionshospitalet Viborg, Skive (1) · Reproductive Medicine Associates of New Jersey (1) · Richard Kordus, PhD, HCLD (ABB) (1) · University of California, San Francisco (1) · Weill Medical College of Cornell University (1)
Egypt (4) · United States (4) · China (1) · India (1) · Spain (1) · Turkey (Türkiye) (1) · Vietnam (1)
Hosam Zaki, MSc, FRCOG (3) · Abd El Ghafar Hussin, BSc (1) · Amr Elshimy, BSc. (1) · Ashok Agarwal, PhD (1) · Carlos Balmori Boticario, PhD (1) · Cherry Yang, MSc (1) · Divreena Talwar, MSc (1) · Do Thuy Huong, PhD candidate (1) · Eman Hasanen, BSc (1) · Eman Hasanen, BSc. (1) · Hanaa Alkhader (1) · Hanaa Alkhader, MBBS/MD (1) · Hanan Ramadan, PhD (1) · Jayesh Shinde, MSc (1) · Jonathan Gal, MD (1)
PMID 24799882, PMID 31081299, PMID 32772268, PMID 33422457, PMID 35522187