5 completed, 1 not yet recruiting. 6 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Snake Bites: new trials by email Literature Review of Snake Bites trials Research Report on Snake Bites
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of Oral Community SVMP INhibitors for Snakebite 2,3-dimercapto-1-propanesulfonic acid, marimastat, Oral placebo capsules - Snakebite | Phase 2 | Not yet recruiting | Liverpool School of Tropical Medicine | 504 | 2027-01-01 | 2026-05-12 |
| Broad-spectrum Rapid Antidote: Varespladib IV to Oral Trial for Snakebite (BRAVIO) Varespladib intravenous form, varespladib-methyl- oral form, Placebo intravenous form - Snakebite, Envenoming, Snake | Phase 2 | Completed | Ophirex, Inc. | 140 | 2023-05-30 | 2025-06-27 |
| Broad-spectrum Rapid Antidote: Varespladib Oral for Snakebite Varespladib Methyl, Placebo, Standard of care (SOC) - Snakebites, Envenoming | Phase 2 | Completed | Ophirex, Inc. | 95 | 2021-08-15 | 2025-07-01 |
| Comparison of Two Dose Regimens of Snake Antivenom for the Treatment of Snake Bites Envenoming in Nepal Antivenom - Snake Bite | Phase 2 | Completed | CTU | 250 | 2011-04-01 | 2017-02-07 |
| A Comparison of Crotalinae Equine Immune F(ab)2 Antivenom (Anavip) and Crotalidae Polyvalent Immune Fab, Anavip, CroFab - Snake Bite, Blood Coagulation Disorders | Phase 2 | Completed | Instituto Bioclon S.A. de C.V. | 12 | 2005-01-01 | 2016-04-18 |
| A Controlled Clinical Trial on The Use of a Specific Antivenom Against Envenoming by Bungarus Multicinctus Bungarus multicinctus-candidus Antivenom, Supportive Care - Snake Bite | Phase 1 / Phase 2 | Completed | Hanoi Medical University | 81 | 2004-03-01 | 2008-12-18 |
Blood Coagulation Disorders (1)
Bites and Stings (6) · Chemically-Induced Disorders (6) · Poisoning (6) · Wounds and Injuries (6) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1)
varespladib methyl (2) · Antivenins (1) · Crotalidae Polyvalent immune Fab (1) · Palliative Care (1) · Standard of Care (1) · Unithiol (1) · anavip (1) · marimastat (1) · varespladib (1)
Ophirex, Inc. (2) · CTU (1) · Hanoi Medical University (1) · Instituto Bioclon S.A. de C.V. (1) · Liverpool School of Tropical Medicine (1)
United States (3) · India (1) · Nepal (1) · Vietnam (1)
David Warrell, MD, PhD (1) · Leslie Boyer, MD (1) · Matthew Lewin, MD, PhD (1) · Sanjib Sharma, MD (1) · Timothy F Platts-Mills, MD, MSc (1) · Timothy Platts-Mills, MD, MSc (1)
PMID 11174237, PMID 11837876, PMID 20358414, PMID 28510574, PMID 31205473, PMID 40738154, PMID 8544231, PMID 9042094, PMID 9509180, PMID 9792162