2 completed, 1 terminated, 1 unknown. 4 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Severe Aplastic Anemia: new trials by email Literature Review of Severe Aplastic Anemia trials Research Report on Severe Aplastic Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) cyclosporine, Matched Unrelated Donor Hematopoetic Stem Cell Transplant, horse anti-thymocyte globulin (ATG) - Severe Aplastic Anemia | Phase 3 | Terminated | Boston Children's Hospital | 53 | 2023-01-25 | 2026-10-19 |
| Hetrombopag or Placebo in Treatment-Naive Severe Aplastic Anemia Hetrombopag Olamine+Standard Therapy, Placebo+Standard Therapy - Severe Aplastic Anemia | Phase 3 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 240 | 2019-03-05 | 2024-11-07 |
| Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients Non ATG Conditioning regimen, GVHD Prophylaxis, Allogenic Stem Cell Transplantation - Severe Aplastic Anemia | Phase 2 / Phase 3 | Unknown | Assiut University | 50 | 2019-01-01 | 2018-11-27 |
| hATG+CsA vs hATG+CsA+Eltrombopag for SAA hATG, CsA, Eltrombopag - Severe Aplastic Anemia | Phase 3 | Completed | European Society for Blood and Marrow Transplantation | 202 | 2015-07-01 | 2026-04-24 |
Anemia, Aplastic (4)
Anemia (4) · Bone Marrow Diseases (4) · Bone Marrow Failure Disorders (4) · Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4)
Antilymphocyte Serum (2) · Cyclophosphamide (1) · Cyclosporine (1) · Immunosuppression Therapy (1) · Methotrexate (1) · Whole-Body Irradiation (1) · eltrombopag (1) · fludarabine (1) · thymoglobulin (1)
Assiut University (1) · Boston Children's Hospital (1) · European Society for Blood and Marrow Transplantation (1) · Jiangsu HengRui Medicine Co., Ltd. (1)
Canada (1) · China (1) · France (1) · Italy (1) · Netherlands (1) · Spain (1) · Switzerland (1) · United Kingdom (1) · United States (1)
Antonio Risitano, MD, PhD (1) · Bronwen Shaw, MD (1) · David Williams, MD (1) · Michael Pulsipher, MD (1) · Regis Peffault de Latour, MD, PhD (1)
PMID 34986284, PMID 38088156, PMID 42047558
1UG3HL157564-01A1 (1), 2014 (1), U24HL157560 (1)