3 terminated, 1 completed, 1 recruiting. 5 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 3, Completed 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Sclerosis, Systemic: new trials by email Literature Review of Sclerosis, Systemic trials Research Report on Sclerosis, Systemic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis UCMSC, Placebo - Sclerosis, Systemic, Mesenchymal Stem Cells | Phase 1 / Phase 2 | Recruiting | Marie Hudson, MD | 18 | 2023-01-05 | 2026-02-03 |
| An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc) HZN-825 - Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic | Phase 2 | Terminated | Amgen | 174 | 2022-11-04 | 2026-01-05 |
| A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis HZN-825 BID, Placebo, HZN-825 QD - Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic | Phase 2 | Terminated | Amgen | 301 | 2021-11-05 | 2026-03-20 |
| Effects of FT011 in Systemic Sclerosis FT011, Placebo - Scleroderma, Systemic, Scleroderma, Diffuse | Phase 2 | Completed | Certa Therapeutics | 30 | 2021-07-19 | 2023-12-20 |
| Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung Disease Pomalidomide (CC-4047), Placebo - Scleroderma, Systemic, Sclerosis, Systemic | Phase 2 | Terminated | Celgene | 23 | 2012-08-09 | 2023-12-01 |
Scleroderma, Systemic (5) · Scleroderma, Diffuse (3) · Lung Diseases, Interstitial (1)
Connective Tissue Diseases (5) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Lung Diseases (1) · Respiratory Tract Diseases (1)
FT011 (1) · pomalidomide (1)
Amgen (2) · Celgene (1) · Certa Therapeutics (1) · Marie Hudson, MD (1)
Spain (4) · Poland (3) · Australia (2) · Italy (2) · Serbia (2) · United Kingdom (2) · United States (2) · Argentina (1) · Canada (1) · Chile (1) · France (1) · Germany (1) · Greece (1) · Israel (1) · Japan (1)
Darren Kelly, PhD (1) · Marie Hudson, MD (1) · Shimon Korish, MD (1)
2023 (1)