3 terminated. 3 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Terminated 3 |
| Phase 3 | 2 | Terminated 2 |
Follow Rett Syndrome: new trials by email Literature Review of Rett Syndrome trials Research Report on Rett Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Open-Label Study of Trofinetide for the Treatment of Girls Two to Five Years of Age Who Have Rett Syndrome Trofinetide - Rett Syndrome | Phase 2 / Phase 3 | Terminated | ACADIA Pharmaceuticals Inc. | 15 | 2021-09-22 | 2024-09-24 |
| Evaluation of the Efficacy, Safety, and Tolerability of Sarizotan in Rett Syndrome With Respiratory Symptoms Sarizotan low dose, Sarizotan high dose, Placebo - Rett Syndrome | Phase 2 / Phase 3 | Terminated | Newron Pharmaceuticals SPA | 129 | 2016-10-26 | 2021-12-21 |
| Trial of Dextromethorphan in Rett Syndrome Dextromethorphan - Rett Syndrome | Phase 2 | Terminated | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 38 | 2004-08-01 | 2014-04-23 |
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Genetic Diseases, X-Linked (3) · Heredodegenerative Disorders, Nervous System (3) · Intellectual Disability (3) · Nervous System Diseases (3) · Neurobehavioral Manifestations (3) · Neurologic Manifestations (3) · X-Linked Intellectual Disability (3)
Dextromethorphan (1) · sarizotan (1) · trofinetide (1)
ACADIA Pharmaceuticals Inc. (1) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (1) · Newron Pharmaceuticals SPA (1)
United States (3) · Australia (1) · India (1) · Italy (1) · United Kingdom (1)
Ravi Anand, MD (1) · SakkuBai Naidu, MD (1)