4 completed, 3 recruiting, 1 active not recruiting, 1 withdrawn. 4 Phase 2, 3 Phase 3, 1 Early Phase 1, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 2, Active not recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Recruiting 2, Active not recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Progesterone Resistance: new trials by email Literature Review of Progesterone Resistance trials Research Report on Progesterone Resistance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy Dienogest 2 MG - Endometriosis | Recruiting | University of Udine | 90 | 2024-04-22 | 2025-04-02 | |
| GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients GnRHa, Letrozole 2.5mg, Diane-35 - Endometrial Neoplasms, Atypical Endometrial Hyperplasia | Phase 2 / Phase 3 | Recruiting | Xiaojun Chen | 80 | 2022-07-13 | 2026-09-10 |
| GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients GnRH antagonist, Letrozole 2.5mg - Endometrial Neoplasms, Atypical Endometrial Hyperplasia | Phase 2 / Phase 3 | Recruiting | Xiaojun Chen | 29 | 2022-07-13 | 2026-09-10 |
| GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients GnRH antagonist, Letrozole 2.5mg - Atypical Endometrial Hyperplasia, Progesterone Resistance | Phase 2 / Phase 3 | Active not recruiting | Xiaojun Chen | 29 | 2022-07-13 | 2025-08-11 |
| SIRT-1 Antagonism for Endometrial Receptivity EX-527 (Selisistat), Placebo - Endometriosis, Uterine Diseases | Phase 2 | Withdrawn | Wake Forest University Health Sciences | 2022-01-01 | 2021-11-17 | |
| Variation of Progesterone in IVF Cycles Progesterone variation - Progesterone Resistance | Completed | ART Fertility Clinics LLC | 30 | 2018-05-10 | 2020-02-26 | |
| Progesterone Supplementation in Threatened Abortion Progesterone, Placebos - Threatened Abortion, Progesterone Resistance | Phase 4 | Completed | Tanta University | 190 | 2018-01-01 | 2023-07-18 |
| Step Down FSH Approach and Late Follicular Phase in Progesterone Level follicle stimulating hormone - Progesterone Resistance | Early Phase 1 | Completed | ART Fertility Clinics LLC | 127 | 2017-11-23 | 2020-09-09 |
| Progesterone Action on Endometrium of PCOS Progesterone 400 Mg Vaginal Suppository on PCOS - Polycystic Ovary, Progesterone Resistance | Not applicable | Completed | University of Sao Paulo General Hospital | 36 | 2014-02-10 | 2022-01-20 |
Endometrial Hyperplasia (3) · Endometrial Neoplasms (2) · Endometriosis (2) · Obesity (2) · Abortion, Threatened (1) · Infertility (1) · Polycystic Ovary Syndrome (1) · Uterine Diseases (1)
Female Urogenital Diseases and Pregnancy Complications (7) · Urogenital Diseases (7) · Female Urogenital Diseases (6) · Genital Diseases (6) · Genital Diseases, Female (6) · Neoplasms (3) · Uterine Diseases (3) · Body Weight (2) · Genital Neoplasms, Female (2) · Neoplasms by Site (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Overnutrition (2) · Overweight (2) · Pathological Conditions, Signs and Symptoms (2)
Letrozole (3) · LHRH, Ac-Nal(1)-Cpa(2)-Trp(3)-Arg(6)-Ala(10)- (2) · Progesterone (2) · 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (1) · Cyproterone acetate, ethinyl estradiol drug combination (1) · Follicle Stimulating Hormone (1) · dienogest (1) · follitropin alfa (1)
Xiaojun Chen (3) · ART Fertility Clinics LLC (2) · Tanta University (1) · University of Sao Paulo General Hospital (1) · University of Udine (1) · Wake Forest University Health Sciences (1)
China (3) · United Arab Emirates (2) · Egypt (1) · Italy (1) · United States (1)
Bruce A Lessey, MD, PhD (1) · Giuseppe Vizzielli, prof (1) · Human Fatemi (1) · Upma Shanker (1)
PMID 21411543, PMID 22249553, PMID 24458485, PMID 25434369, PMID 25554522, PMID 26806353, PMID 31242330, PMID 31824423, PMID 31905164, PMID 33927696