9 completed. 9 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 9 |
| Phase 1 | 1 | Completed 1 |
Follow Mucosal Melanoma: new trials by email Literature Review of Mucosal Melanoma trials Research Report on Mucosal Melanoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess YH003 in Combination with Pebolizumab and Albumin Paclitaxel Injection in Subjects with Unresectable/metastatic Mucosal Melanoma YH003, Pembrolizumab, albumin paclitaxel - Mucosal Melanoma | Phase 2 | Completed | Eucure (Beijing) Biopharma Co., Ltd | 20 | 2022-06-13 | 2025-01-06 |
| Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma Ipilimumab, Nivolumab - Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | Phase 2 | Completed | National Cancer Institute (NCI) | 94 | 2017-10-23 | 2025-01-13 |
| Neoadjuvant and Adjuvant Checkpoint Blockade Ipilimumab, Laboratory Biomarker Analysis, Nivolumab - Cutaneous Melanoma, Mucosal Melanoma | Phase 2 | Completed | M.D. Anderson Cancer Center | 53 | 2016-02-02 | 2024-04-05 |
| Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists Peptide Vaccine (LPV7) + Tetanus peptide, PolyICLC, Resiquimod - Melanoma, Metastatic Melanoma | Phase 1 / Phase 2 | Completed | Craig L Slingluff, Jr | 50 | 2014-05-01 | 2024-02-28 |
| A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Recombinant Flt3 Ligand - Cutaneous Melanoma, Melanoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2014-04-09 | 2021-11-16 |
| Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery Bevacizumab, Ipilimumab, Laboratory Biomarker Analysis - Metastatic Melanoma, Mucosal Melanoma | Phase 2 | Completed | Academic and Community Cancer Research United | 24 | 2013-10-18 | 2020-01-21 |
| Epacadostat and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma Epacadostat, MELITAC 12.1 Peptide Vaccine - Mucosal Melanoma, Recurrent Melanoma | Phase 2 | Completed | Fred Hutchinson Cancer Center | 11 | 2013-09-13 | 2018-06-08 |
| Imatinib in Patients With Mucosal or Acral/Lentiginous Melanoma Imatinib - Mucosal Melanoma, Acral/Lentiginous Melanoma | Phase 2 | Completed | Dana-Farber Cancer Institute | 24 | 2006-07-01 | 2016-12-08 |
| Vaccine Therapy in Treating Patients With Stage IIC-IV Melanoma gp100 antigen, tyrosinase peptide, recombinant MAGE-3.1 antigen - Ciliary Body and Choroid Melanoma, Medium/Large Size, Ciliary Body and Choroid Melanoma, Small Size | Phase 2 | Completed | University of Southern California | 42 | 2004-05-01 | 2014-05-22 |
Melanoma (6) · Uveal Melanoma (5) · Neoplasms (1)
Neoplasms by Histologic Type (6) · Neoplasms by Site (6) · Neoplasms, Germ Cell and Embryonal (6) · Neoplasms, Nerve Tissue (6) · Neuroectodermal Tumors (6) · Neuroendocrine Tumors (6) · Nevi and Melanomas (6) · Skin Diseases (6) · Skin Neoplasms (6) · Skin and Connective Tissue Diseases (6) · Eye Diseases (5) · Eye Neoplasms (5) · Neoplasms (5) · Uveal Diseases (5) · Uveal Neoplasms (5)
CTLA-4 Antigen (3) · Ipilimumab (3) · Disulfides (2) · Immunoglobulin G (2) · Nivolumab (2) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · Bevacizumab (1) · Imatinib Mesylate (1) · MAGEA3 protein, human (1) · ProMune (1) · Protein Subunit Vaccines (1) · Taxes (1) · epacadostat (1) · flt3 ligand protein (1)
National Cancer Institute (NCI) (2) · Academic and Community Cancer Research United (1) · Craig L Slingluff, Jr (1) · Dana-Farber Cancer Institute (1) · Eucure (Beijing) Biopharma Co., Ltd (1) · Fred Hutchinson Cancer Center (1) · M.D. Anderson Cancer Center (1) · University of Southern California (1)
United States (8) · China (1)
Ari M Vanderwalde (1) · Craig L Slingluff, Jr., M.D. (1) · Craig Slingluff (1) · F. Stephen Hodi, MD (1) · Jeffrey Weber (1) · Nina Bhardwaj (1) · Rodabe N Amaria (1) · Svetomir N Markovic (1)
PMID 25609545, PMID 34413169, PMID 35121932, PMID 36648215, PMID 37592104, PMID 40638872
U01CA154967 (2), P30CA015083 (1), P30CA015704 (1), U10CA180888 (1)