3 not yet recruiting, 2 recruiting, 1 terminated. 3 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 3 | Not yet recruiting 2, Recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Metastatic Castration-Resistant Prostate Adenocarcinoma: new trials by email Literature Review of Metastatic Castration-Resistant Prostate Adenocarcinoma trials Research Report on Metastatic Castration-Resistant Prostate Adenocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial Lutetium Lu 177 Vipivotide Tetraxetan, Cell-free Circulating Tumor DNA Assay, Computed Tomography - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | University of Washington | 64 | 2026-11-15 | 2026-10-19 |
| Pluvicto for the Treatment of African American Men With Metastatic Castration-Resistant Prostate Cancer Biopsy Procedure, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Not yet recruiting | Emory University | 88 | 2026-11-02 | 2026-10-06 |
| IL-18 Armored STEAP1 CAR T Cells for the Treatment of Metastatic Castration Resistant Prostate Cancer FH-STEAP1 IL-18 CAR T cells, Antiandrogen Therapy, Biospecimen Collection - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 1 | Not yet recruiting | Fred Hutchinson Cancer Center | 20 | 2026-10-31 | 2026-09-04 |
| 177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer Biospecimen Collection, Bone Scan, Computed Tomography - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 1 | Recruiting | City of Hope Medical Center | 30 | 2026-03-06 | 2026-04-20 |
| First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant Prostate Cancer CCW702 - Metastatic Castration-Resistant Prostate Adenocarcinoma | Phase 1 | Terminated | Calibr, a division of Scripps Research | 22 | 2020-07-17 | 2023-05-12 |
Genital Diseases (5) · Genital Diseases, Male (5) · Genital Neoplasms, Male (5) · Male Urogenital Diseases (5) · Neoplasms (5) · Neoplasms by Site (5) · Prostatic Diseases (5) · Urogenital Diseases (5) · Urogenital Neoplasms (5)
Specimen Handling (5) · Pluvicto (4) · Glutamate Carboxypeptidase II (3) · Magnetic Resonance Spectroscopy (3) · Biopsy (2) · Docetaxel (2) · Leukapheresis (2) · Abiraterone Acetate (1) · Androgen Antagonists (1) · Calcium Dobesilate (1) · Cyclophosphamide (1) · Dexamethasone (1) · Drug Therapy (1) · Medrol Veriderm (1) · Methylprednisolone (1)
Calibr, a division of Scripps Research (1) · City of Hope Medical Center (1) · ECOG-ACRIN Cancer Research Group (1) · Emory University (1) · Fred Hutchinson Cancer Center (1) · University of Washington (1)
United States (5)
Alex Chehrazi-Raffle, MD (1) · Jacob E Berchuck, MD (1) · Michael Schweizer (1) · Michael Schweizer, MD (1) · Rosa Nadal Rios, MD, PhD (1)
P30CA033572 (1), P30CA138292 (1), U10CA180820 (1)