28 completed, 9 terminated, 6 recruiting, 5 withdrawn. 16 Phase 2, 14 Phase 1, 9 Phase 3, 5 Not applicable, 1 Early Phase 1.
Follow Lymphoproliferative Disorder: new trials by email Literature Review of Lymphoproliferative Disorder trials Research Report on Lymphoproliferative Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD) Biospecimen Collection, Bone Marrow Aspiration, Electronic Health Record Review - Lymphoproliferative Disorder, Multiple Myeloma | Not applicable | Recruiting | Mayo Clinic | 82 | 2024-11-22 | 2026-10-01 |
| Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas Acalabrutinib, Obinutuzumab, Quality-of-Life Assessment - Grade 1 Follicular Lymphoma, Grade 2 Follicular Lymphoma | Phase 2 | Recruiting | Emory University | 49 | 2021-09-03 | 2026-02-09 |
| Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas Nivolumab - Epstein-Barr Virus Infections, Lymphoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 40 | 2018-04-26 | 2026-10-16 |
| Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Busulfan, Cyclophosphamide - Hematopoietic and Lymphoid Cell Neoplasm, High Risk Acute Myeloid Leukemia | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 204 | 2016-08-05 | 2026-08-06 |
| Project: Every Child for Younger Patients With Cancer Cytology Specimen Collection Procedure, Medical Chart Review - Adrenal Gland Pheochromocytoma, Carcinoma In Situ | Recruiting | Children's Oncology Group | 75000 | 2015-11-03 | 2026-08-25 | |
| 3rd Party LMP1/2-Specific Cytotoxic T Lymphocytes for EBV-Associated Lymphoma EBV CTL's, Peripheral Blood Donor - Non-Hodgkins Lymphoma, Hodgkins Lymphoma | Phase 1 | Completed | New York Medical College | 1 | 2014-01-01 | 2017-12-22 |
| Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases LMP specific T cells - Hodgkin Lymphoma, Non-Hodgkin Lymphoma | Phase 1 | Completed | Baylor College of Medicine | 37 | 2012-02-01 | 2020-02-07 |
| Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma imetelstat sodium, laboratory biomarker analysis, pharmacological study - Brain and Central Nervous System Tumors, Lymphoma | Phase 1 | Completed | Children's Oncology Group | 34 | 2011-05-01 | 2014-01-30 |
| Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant anti-thymocyte globulin, donor lymphocytes, filgrastim - Leukemia, Lymphoma | Phase 2 | Terminated | Alliance for Clinical Trials in Oncology | 6 | 2010-12-01 | 2017-03-24 |
| Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation anti-thymocyte globulin, rituximab, sirolimus - Chronic Myeloproliferative Disorders, Graft Versus Host Disease | Phase 2 | Terminated | Barbara Ann Karmanos Cancer Institute | 4 | 2010-08-01 | 2019-03-26 |
| Registry of Older Patients With Cancer Chronic Myeloproliferative Disorders, Cognitive/Functional Effects | Recruiting | UNC Lineberger Comprehensive Cancer Center | 3000 | 2009-09-01 | 2026-06-29 | |
| 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer 3'-deoxy-3'-[18F]fluorothymidine - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Active not recruiting | Barbara Ann Karmanos Cancer Institute | 2009-09-01 | 2026-08-10 | ||
| Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer biologic sample preservation procedure, cytology specimen collection procedure - Chronic Myeloproliferative Disorders, Leukemia | Recruiting | UNC Lineberger Comprehensive Cancer Center | 15000 | 2009-07-01 | 2025-10-27 | |
| Bortezomib and Rituximab in Treating Patients With Post-Transplant Lymphoproliferative Disorders rituximab, bortezomib - Lymphoproliferative Disorder | Phase 2 | Terminated | Masonic Cancer Center, University of Minnesota | 3 | 2009-03-01 | 2017-12-05 |
| Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer methadone hydrochloride, morphine sulfate, oxycodone hydrochloride - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Not applicable | Terminated | M.D. Anderson Cancer Center | 1 | 2009-03-01 | 2020-09-24 |
| Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer donor natural killer cell infusion - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Phase 1 / Phase 2 | Completed | Asan Medical Center | 47 | 2009-01-01 | 2013-02-20 |
| Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone chemotherapy, dapsone, medical chart review - Chronic Myeloproliferative Disorders, Leukemia | Completed | Vanderbilt University | 41 | 2009-01-01 | 2017-04-17 | |
| Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers cytology specimen collection procedure, fluorescent antibody technique, assessment of therapy complications - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Not applicable | Terminated | City of Hope Medical Center | 9 | 2008-11-01 | 2015-06-08 |
| American Ginseng in Treating Patients With Fatigue Caused by Cancer American ginseng, placebo - Chronic Myeloproliferative Disorders, Fatigue | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 364 | 2008-10-01 | 2017-02-09 |
| Quality of Life in Younger Leukemia and Lymphoma Survivors telephone-based intervention, questionnaire administration, assessment of therapy complications - Anxiety Disorder, Cancer Survivor | Completed | Case Comprehensive Cancer Center | 48 | 2008-10-01 | 2011-08-24 |
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Lymphoproliferative Disorders (52) · Lymphoma (39) · Hodgkin Disease (35) · Lymphoma, Non-Hodgkin (33) · Burkitt Lymphoma (32) · Lymphoma, Follicular (31) · Lymphoma, Mantle-Cell (31) · Immunoblastic Lymphadenopathy (30) · Leukemia, Lymphocytic, Chronic, B-Cell (30) · Lymphoma, B-Cell, Marginal Zone (30) · Lymphoma, Large B-Cell, Diffuse (30) · Lymphoma, Large-Cell, Anaplastic (30) · Lymphoma, T-Cell, Cutaneous (30) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (30) · Lymphoma, Large-Cell, Immunoblastic (29)
Hemic and Lymphatic Diseases (52) · Immune System Diseases (52) · Immunoproliferative Disorders (52) · Lymphatic Diseases (51) · Neoplasms by Histologic Type (45) · Neoplasms (40) · Hematologic Diseases (36) · Lymphoma, B-Cell (36) · Pathological Conditions, Signs and Symptoms (36) · DNA Virus Infections (34) · Herpesviridae Infections (34) · Infections (34) · Tumor Virus Infections (34) · Virus Diseases (34) · Disease Attributes (33)
Rituximab (6) · Cyclophosphamide (4) · Epoetin Alfa (4) · Bortezomib (3) · Darbepoetin alfa (3) · Prednisone (3) · Tacrolimus (3) · Antilymphocyte Serum (2) · Busulfan (2) · Doxorubicin (2) · Early Intervention, Educational (2) · Etoposide (2) · Filgrastim (2) · Methotrexate (2) · Mycophenolic Acid (2)
Alliance for Clinical Trials in Oncology (4) · Children's Oncology Group (4) · Jonsson Comprehensive Cancer Center (4) · Mayo Clinic (4) · M.D. Anderson Cancer Center (3) · National Cancer Institute (NCI) (3) · Barbara Ann Karmanos Cancer Institute (2) · Case Comprehensive Cancer Center (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · UNC Lineberger Comprehensive Cancer Center (2) · Vanderbilt-Ingram Cancer Center (2) · Asan Medical Center (1) · Baylor College of Medicine (1) · Cancer Research UK (1)
United States (46) · Canada (5) · Australia (3) · New Zealand (2) · Puerto Rico (2) · United Kingdom (2) · Saudi Arabia (1) · South Korea (1)
Christopher J Melani, M.D. (2) · Debra Barton, RN, PhD, AOCN, FAAN (2) · John A. Glaspy, MD, MPH (2) · Adam J. Esbenshade, MD (1) · Alex A. Adjei, MD, PhD (1) · Amanda M Termuhlen (1) · Anne H. Blaes, MD (1) · Anthony F. Shields, MD, PhD (1) · Aprille Seidel, PhD (1) · Asad Bashey, MD, PhD (1) · Barbara A. Murphy, MD (1) · Carlos A Ramos, MD (1) · Carolyn Britten, MD (1) · Catherine Bollard, MD (1) · Charles L. Loprinzi, M.D. (1)
PMID 16505427, PMID 16710026, PMID 18293016, PMID 19170225, PMID 20142598, PMID 20166206, PMID 20229590, PMID 20496177, PMID 21135857, PMID 21247755, PMID 21479990, PMID 21487108, PMID 22883417, PMID 24174627, PMID 25331113, PMID 25921059, PMID 26175532, PMID 26700120, PMID 26700123, PMID 30205939, PMID 33720337, PMID 37011643, PMID 37611156, PMID 38941593, PMID 41845569
P30CA015083 (3), U10CA098543 (3), P30CA006973 (2), P30CA016086 (2), P30CA022453 (2), P30CA068485 (2), P30CA008748 (1), P30CA033572 (1), P30CA043703 (1), P30CA072720 (1), P30CA138292 (1), R01CA127655 (1), UG1CA189958 (1)