2 completed. 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Locally Advanced Malignant Solid Neoplasm: new trials by email Literature Review of Locally Advanced Malignant Solid Neoplasm trials Research Report on Locally Advanced Malignant Solid Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers Pembrolizumab - Locally Advanced Malignant Solid Neoplasm | Phase 2 | Completed | M.D. Anderson Cancer Center | 35 | 2019-10-31 | 2025-05-13 |
| Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer Biopsy, Biospecimen Collection, Computed Tomography - Hematopoietic and Lymphoid Cell Neoplasm, Locally Advanced Malignant Solid Neoplasm | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 27 | 2013-10-08 | 2025-01-14 |
Hematologic Neoplasms (1) · Melanoma (1) · Neoplasm Metastasis (1)
Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms by Site (1) · Neoplasms, Germ Cell and Embryonal (1) · Neoplasms, Nerve Tissue (1) · Neoplastic Processes (1) · Neuroectodermal Tumors (1) · Neuroendocrine Tumors (1) · Nevi and Melanomas (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Skin Diseases (1) · Skin Neoplasms (1)
Biopsy (1) · GSK2141795 (1) · Magnetic Resonance Spectroscopy (1) · Specimen Handling (1) · dabrafenib (1) · pembrolizumab (1) · trametinib (1)
M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1)
United States (2)
Antoni Ribas (1) · Michael J Overman, MD (1)
PMID 33416261, PMID 36623241, PMID 38261444
U10CA032102 (1), U10CA180830 (1), U10CA180888 (1)