3 recruiting, 1 active not recruiting, 1 not yet recruiting. 2 Phase 1, 2 Phase 2, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Locally Advanced Intrahepatic Cholangiocarcinoma: new trials by email Literature Review of Locally Advanced Intrahepatic Cholangiocarcinoma trials Research Report on Locally Advanced Intrahepatic Cholangiocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer Biospecimen Collection, Cisplatin, Computed Tomography - Locally Advanced Biliary Tract Adenocarcinoma, Locally Advanced Extrahepatic Cholangiocarcinoma | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 336 | 2027-01-11 | 2026-08-14 |
| Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma Biospecimen Collection, Cisplatin, Computed Tomography - Locally Advanced Ampulla of Vater Carcinoma, Locally Advanced Biliary Tract Carcinoma | Phase 2 | Recruiting | Ohio State University Comprehensive Cancer Center | 29 | 2026-11-01 | 2026-09-10 |
| Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma After SIRT and Chemotherapy Liver transplant - Intrahepatic Cholangiocarcinoma, Locally Advanced Intrahepatic Cholangiocarcinoma | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 36 | 2025-08-28 | 2026-04-06 |
| Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma Angiography, Biopsy, Biospecimen Collection - Locally Advanced Intrahepatic Cholangiocarcinoma, Oligometastatic Intrahepatic Cholangiocarcinoma | Phase 1 | Recruiting | Mayo Clinic | 16 | 2024-06-06 | 2026-05-13 |
| Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma Bintrafusp Alfa, Biopsy, Hypofractionated Radiation Therapy - Locally Advanced Intrahepatic Cholangiocarcinoma, Metastatic Intrahepatic Cholangiocarcinoma | Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 2 | 2021-08-31 | 2026-09-14 |
Cholangiocarcinoma (5) · Gallbladder Neoplasms (1)
Adenocarcinoma (5) · Carcinoma (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Biliary Tract Diseases (1) · Biliary Tract Neoplasms (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gallbladder Diseases (1) · Neoplasms by Site (1)
Disulfides (3) · Immunoglobulin G (3) · Magnetic Resonance Spectroscopy (3) · Specimen Handling (3) · durvalumab (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Biopsy (2) · Cisplatin (2) · Gemcitabine (2) · Platinum (2) · Cerebral Angiography (1) · Liver Transplantation (1) · Radiation Dose Hypofractionation (1) · bintrafusp alfa protein, human (1) · pembrolizumab (1)
Assistance Publique - Hôpitaux de Paris (1) · ECOG-ACRIN Cancer Research Group (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Ohio State University Comprehensive Cancer Center (1)
United States (3) · France (1)
Deirdre J Cohen (1) · Eugene J Koay (1) · Mohamed Bouattour (1) · Sameek Roychowdhury, MD, PhD (1) · Umair Majeed, MD (1)
U10CA180820 (1)