3 completed. 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
Follow Epidermolysis Bullosa Simplex: new trials by email Literature Review of Epidermolysis Bullosa Simplex trials Research Report on Epidermolysis Bullosa Simplex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Topical TolaSure Targeting Aggregated Mutant Keratin in Severe Epidermolysis Bullosa Simplex TolaSure Topical Gel, Vehicle Topical Gel - Epidermolysis Bullosa Simplex | Phase 1 | Completed | BioMendics, LLC | 6 | 2022-05-05 | 2023-09-11 |
| To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB) Diacerein 1% Ointment - Epidermolysis Bullosa (EB), Epidermolysis Bullosa Simplex | Phase 1 | Completed | Castle Creek Pharmaceuticals, LLC | 11 | 2018-05-18 | 2020-02-10 |
| Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin Jojoba oil with broccoli sprout extract, Jojoba oil (placebo) - Epidermolysis Bullosa Simplex, Pachyonychia Congenita | Phase 1 | Completed | Johns Hopkins University | 5 | 2015-09-01 | 2017-12-06 |
Epidermolysis Bullosa (2) · Epidermolysis Bullosa Dystrophica (1) · Epidermolysis Bullosa, Junctional (1) · Pachyonychia Congenita (1) · Skin Abnormalities (1) · Skin Diseases (1)
Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Skin Diseases, Genetic (3) · Skin Diseases, Vesiculobullous (3) · Skin and Connective Tissue Diseases (3) · Skin Abnormalities (2) · Skin Diseases (2) · Abnormalities, Multiple (1) · Collagen Diseases (1) · Connective Tissue Diseases (1) · Ectodermal Dysplasia (1) · Epidermolysis Bullosa (1) · Nail Diseases (1)
Ointments (1) · diacerein (1) · jojoba wax (1)
BioMendics, LLC (1) · Castle Creek Pharmaceuticals, LLC (1) · Johns Hopkins University (1)
United States (3)
Bernard Cohen, MD (1) · Mary Spellman (1)