2 completed, 1 active not recruiting, 1 recruiting. 3 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Corneal Endothelial Dysfunction: new trials by email Literature Review of Corneal Endothelial Dysfunction trials Research Report on Corneal Endothelial Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction Combination Product: AURN001 + Y-27632, Placebo - Corneal Edema, Corneal Endothelial Dysfunction | Phase 3 | Active not recruiting | Aurion Biotech | 130 | 2026-02-19 | 2026-09-24 |
| PVEK Corneal Implant For Treatment of Corneal Edema Precise Vision Endothelial Keratoplasty (PVEK) Implant - Corneal Edema, Fuchs' Endothelial Dystrophy | Phase 1 | Recruiting | Precise Bio | 15 | 2025-09-16 | 2026-01-12 |
| A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1) AURN001, Corneal Endothelial Cells, Y27632 - Corneal Edema, Corneal Endothelial Dysfunction | Phase 1 / Phase 2 | Completed | Aurion Biotech | 97 | 2023-10-18 | 2025-12-17 |
| Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema EO2002, EO2002 low dose, EO2002 mid dose - Corneal Edema, Corneal Endothelial Dysfunction | Phase 1 | Completed | Emmecell | 42 | 2021-06-22 | 2025-03-05 |
Corneal Edema (4) · Fuchs' Endothelial Dystrophy (2) · Corneal Dystrophy, Posterior Polymorphous, 1 (1)
Corneal Diseases (4) · Eye Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Corneal Dystrophies, Hereditary (2) · Eye Diseases, Hereditary (2) · Genetic Diseases, Inborn (2)
Y 27632 (2) · Drug Implants (1)
Aurion Biotech (2) · Emmecell (1) · Precise Bio (1)
United States (3) · Armenia (1) · Canada (1) · Israel (1)
Michael Minouni, Prof. (1) · Noelia Kunzevitzky (1)