5 recruiting. 5 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Recruiting 5 |
| Phase 2 | 4 | Recruiting 4 |
Follow CLL: new trials by email Literature Review of CLL trials Research Report on CLL
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter, Single-Arm Exploratory Phase I Clinical Study (Assessment of Safety and Efficacy) of Fully Human BAFF-R Chimeric Antigen Receptor T-Cell Injection in Relapsed/Refractory BAFF-R-Positive B-Cell Lymphoma BAFF-R CAR-T - DLBCL, CLL | Phase 1 / Phase 2 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 20 | 2025-11-29 | 2026-05-13 |
| A Phase I Dose Finding Study of MB-CART2219.1 CAR-T cells targeting CD19 and CD22 - Lymphoma, CLL | Phase 1 | Recruiting | University Hospital Tuebingen | 36 | 2025-06-23 | 2025-08-07 |
| A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers. Sonrotoclax, Zanubrutinib - Chronic Lymphocytic Leukemia, CLL | Phase 1 / Phase 2 | Recruiting | BeOne Medicines | 258 | 2025-01-23 | 2026-10-26 |
| Safety and Efficacy of KLS-1 Monotherapy in Malignant Neoplasms Zinc-64 Aspartate - CLL, Solid Tumor, Adult | Phase 1 / Phase 2 | Recruiting | Vector Vitale LLC | 36 | 2024-05-15 | 2026-08-05 |
| Allogeneic CARCIK-CD19 in Adults/Pediatric B-cell NHL or Chronic Lymphocytic Leukemia CARCIK-CD19 - B-cell NHL, CLL | Phase 1 / Phase 2 | Recruiting | Fondazione Matilde Tettamanti Menotti De Marchi Onlus | 29 | 2023-12-01 | 2024-05-03 |
Leukemia, Lymphocytic, Chronic, B-Cell (2) · Hematologic Neoplasms (1) · Lymphoma (1) · Lymphoma, Mantle-Cell (1) · Melanoma (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Pancreatic Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Prostatic Neoplasms (1)
Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Immune System Diseases (3) · Immunoproliferative Disorders (3) · Leukemia (3) · Leukemia, Lymphoid (3) · Lymphatic Diseases (3) · Lymphoproliferative Disorders (3) · Neoplasms by Histologic Type (3) · Chronic Disease (2) · Disease Attributes (2) · Leukemia, B-Cell (2) · Neoplasms (2) · Neoplasms by Site (2) · Pathologic Processes (2)
zanubrutinib (1)
BeOne Medicines (1) · Fondazione Matilde Tettamanti Menotti De Marchi Onlus (1) · Institute of Hematology & Blood Diseases Hospital, China (1) · University Hospital Tuebingen (1) · Vector Vitale LLC (1)
China (2) · Australia (1) · Brazil (1) · France (1) · Germany (1) · Italy (1) · Ukraine (1) · United Kingdom (1) · United States (1)
Andrea Biondi, MD (1) · Grygorii Ursol, MD, PhD (1) · Prof. Valerii Cheshuk, MD, PhD (1)