4 completed, 1 unknown. 3 Phase 2, 2 Phase 3, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Classic Galactosemia: new trials by email Literature Review of Classic Galactosemia trials Research Report on Classic Galactosemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AT-007 in Adult Subjects With Classic Galactosemia (CG) AT-007 - Classic Galactosemia | Phase 3 | Unknown | Applied Therapeutics, Inc. | 7 | 2021-10-01 | 2022-06-14 |
| Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia AT-007, Placebo - Classic Galactosemia | Phase 2 / Phase 3 | Completed | Applied Therapeutics, Inc. | 47 | 2021-03-20 | 2025-10-29 |
| Safety and Pharmacokinetics of AT-007 in Healthy Subjects and in Adult Subjects With Classic Galactosemia AT-007, Placebo - Classic Galactosemia | Phase 1 / Phase 2 | Completed | Applied Therapeutics, Inc. | 114 | 2019-06-21 | 2024-05-30 |
| Preventing Speech and Language Disorders in Children With Classic Galactosemia Babble Boot Camp - Classic Galactosemia, Speech Disorders in Children | Early Phase 1 | Completed | Arizona State University | 285 | 2019-05-01 | 2026-01-23 |
| The Effect of Arginine on Classic Galactosemia Arginine Aspartate - Classic Galactosemia | Phase 2 | Completed | Academisch Ziekenhuis Maastricht | 4 | 2017-12-05 | 2018-09-27 |
Galactosemias (5)
Brain Diseases (5) · Brain Diseases, Metabolic (5) · Brain Diseases, Metabolic, Inborn (5) · Carbohydrate Metabolism, Inborn Errors (5) · Central Nervous System Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Genetic Diseases, Inborn (5) · Metabolic Diseases (5) · Metabolism, Inborn Errors (5) · Nervous System Diseases (5) · Nutritional and Metabolic Diseases (5)
Applied Therapeutics, Inc. (3) · Academisch Ziekenhuis Maastricht (1) · Arizona State University (1)
United States (4) · Netherlands (1)
Jonathan W Mink, MD (1) · Robert Green, MD, MPH (1) · Susan E Waisbren, PhD (1)
PMID 30477550, PMID 32566130, PMID 34665663, PMID 35677809, PMID 36251874, PMID 37146603, PMID 37235746, PMID 38988185, PMID 39569553