4 completed. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
Follow BRCA2 Mutation Carrier: new trials by email Literature Review of BRCA2 Mutation Carrier trials Research Report on BRCA2 Mutation Carrier
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy Telapristone Acetate, Placebo, Laboratory Biomarker Analysis - BRCA1 Mutation Carrier, BRCA2 Mutation Carrier | Phase 2 | Completed | Northwestern University | 67 | 2015-10-01 | 2023-02-22 |
| Veliparib in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Laboratory Biomarker Analysis, Veliparib - BRCA1 Mutation Carrier, BRCA2 Mutation Carrier | Phase 2 | Completed | National Cancer Institute (NCI) | 52 | 2012-04-09 | 2019-07-23 |
| Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer rucaparib (CO-338; formally AG-014699 or PF-01367338), protein expression analysis, western blotting - brca1 Mutation Carrier, brca2 Mutation Carrier | Phase 2 | Completed | Cancer Research UK | 78 | 2007-12-01 | 2016-05-24 |
| Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer carboplatin, docetaxel - brca1 Mutation Carrier, brca2 Mutation Carrier | Phase 2 | Completed | University College London Hospitals | 148 | 2005-09-01 | 2013-08-26 |
Breast Neoplasms (3) · Ovarian Neoplasms (2) · Breast Carcinoma In Situ (1) · Carcinoma, Intraductal, Noninfiltrating (1) · Carcinoma, Ovarian Epithelial (1) · Fallopian Tube Neoplasms (1) · Hereditary Breast and Ovarian Cancer Syndrome (1)
Neoplasms (4) · Neoplasms by Site (4) · Adnexal Diseases (3) · Breast Diseases (3) · Endocrine Gland Neoplasms (3) · Endocrine System Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Genital Diseases, Female (3) · Genital Neoplasms, Female (3) · Gonadal Disorders (3) · Ovarian Diseases (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3)
Blotting, Western (1) · Carboplatin (1) · Chromatography, Liquid (1) · Docetaxel (1) · Immunohistochemistry (1) · Mass Spectrometry (1) · rucaparib (1) · telapristone acetate (1) · veliparib (1)
Cancer Research UK (1) · National Cancer Institute (NCI) (1) · Northwestern University (1) · University College London Hospitals (1)
United Kingdom (2) · United States (2) · Australia (1) · Israel (1) · Portugal (1) · Spain (1) · Sweden (1)
Andrew Tutt, MD, PhD, FRCR, MBBS, MRCP (1) · Robert Coleman (1) · Ruth Plummer (1) · Seema Khan (1)
U10CA027469 (1), U10CA180868 (1)