Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)

NCT07044037 — Completed, 53 participants, Centre Hospitalier de Saint-Denis

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Registry	NCT07044037
Status	Completed
Study type	Observational
Enrollment	53 (Actual)
Sponsor	Centre Hospitalier de Saint-Denis (Other)
Conditions	Toxoplasmosis, Cerebral, Toxoplasmosis, Meningitis, HIV Infections, Cerebrospinal Fluid, Central Nervous System Infections
Dates	start 2024-07-01, primary completion 2024-12-31, completion 2024-12-31, first posted 2025-06-29, last updated 2025-06-29
Locations	1 site in France

-Summary

This study looks at patients who were treated for cerebral toxoplasmosis at CHSD between 2004 and 2024. It focuses on analyzing their cerebrospinal fluid (CSF) to better understand the biological signs of the disease. The goal is to see if CSF results can show signs of meningitis, even though it's not commonly reported, and to describe any co-infections, symptoms, brain imaging findings, and patient outcomes.

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+Outcome measures

Primary outcomes

Number of participants with treatment-related adverse events as assessed by CTCAE v4.0 [From hospital admission to completion of diagnostic lumbar puncture and initial treatment (typically within the first 7 days of hospitalization).]

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

\- Adult patients (age 18 years) hospitalized at CHSD between January 1, 2004 and March 31, 2024 for cerebral toxoplasmosis

Exclusion Criteria:

\- Under 18 years ols

+Locations (1)

Facility	City	Country	Status
France	Saint-Denis, France	France

My Notes

Public

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