2 completed, 1 terminated. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. THR-687 dose level 1, THR-687 dose level 2, THR-687 selected dose level - Diabetes Mellitus, Diabetic Retinopathy | Phase 2 | Terminated | Oxurion | 16 | 2021-08-27 | 2023-08-18 |
| A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema THR-149 dose level 1, THR-149 dose level 2, THR-149 dose level 3 - Diabetes Mellitus, Diabetic Retinopathy | Phase 2 | Completed | Oxurion | 135 | 2020-07-31 | 2023-11-27 |
| A Study to Evaluate THR-317 and Ranibizumab Combination Treatment for Diabetic Macular Oedema (DME) Ranibizumab 0.5mg, THR-317 8mg, Sham injection - Diabetes Mellitus, Diabetic Retinopathy | Phase 2 | Completed | Oxurion | 70 | 2018-04-20 | 2019-08-02 |
Diabetes Mellitus (3) · Diabetic Retinopathy (3) · Macular Edema (1)
aflibercept (2) · Ranibizumab (1) · TB-403 (1) · salicylhydroxamic acid (1)
France (2) · Germany (2) · Slovakia (2) · Spain (2) · United Kingdom (2) · United States (2) · Belgium (1) · Czechia (1) · Estonia (1) · Hungary (1) · Italy (1) · Latvia (1) · Lithuania (1) · Switzerland (1)
2017 (1), 2019 (1)