6 completed, 1 withdrawn. 5 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Withdrawn 1 |
| Phase 1 | 3 | Completed 3 |
Follow Nerre Therapeutics Ltd.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis Orvepitant Maleate, Placebo - Cough, Idiopathic Pulmonary Fibrosis | Phase 2 | Completed | Nerre Therapeutics Ltd. | 80 | 2022-08-01 | 2025-11-10 |
| Mass Balance Study of [14C]-Orvepitant Oral Solution in Healthy Male Subjects [14C]-orvepitant - Healthy | Phase 1 | Completed | Nerre Therapeutics Ltd. | 6 | 2020-06-01 | 2020-08-07 |
| A Study of BAY3427080 (NT-814) in the Treatment of Moderate to Severe Post-menopausal Vasomotor Symptoms Elinzanetant (BAY3427080), Placebo - Menopause, Hot Flashes | Phase 2 | Completed | Bayer | 199 | 2018-11-20 | 2023-03-10 |
| A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers Orvepitant, Itraconazole - Pharmacokinetic Study in Healthy Male Volunteers | Phase 1 | Completed | Nerre Therapeutics Ltd. | 16 | 2018-06-08 | 2018-10-11 |
| A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitis Orvepitant, Placebo - Pruritus, Atopic Dermatitis | Phase 2 | Withdrawn | Nerre Therapeutics Ltd. | 2018-05-01 | 2018-05-15 | |
| A Dose-ranging Study of Orvepitant in Patients With Chronic Refractory Cough Orvepitant Maleate, Placebo - Chronic Refractory Cough | Phase 2 | Completed | Nerre Therapeutics Ltd. | 315 | 2017-05-22 | 2022-04-26 |
| Evaluation of the Pharmacokinetics and Safety of BAY3427080 (NT-814) in Post-Menopausal Women With Vasomotor Symptoms BAY3427080, Placebo (for BAY3427080) - Post-menopausal Vasomotor Symptoms | Phase 1 / Phase 2 | Completed | Bayer | 76 | 2016-08-01 | 2025-02-07 |
Hot Flashes (2) · Cough (1) · Dermatitis, Atopic (1) · Idiopathic Pulmonary Fibrosis (1) · Pruritus (1)
orvepitant (3) · Itraconazole (1)
United Kingdom (5) · United States (4) · Canada (2) · Netherlands (1)
Prof. S. Birring, MB ChB, MD (1)
2018 (1)