2 completed, 1 not yet recruiting, 1 terminated, 1 withdrawn. 4 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 1, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma Lymphodepletion, TCR-T cells (MDG1015) - Epithelial Ovarian Cancer, Gastro-esophageal Junction Cancer | Phase 1 | Not yet recruiting | Medigene AG | 55 | 2025-07-01 | 2024-12-27 |
| HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell Transplantation MDG1021 dose 1, MDG1021 dose 2, MDG1021 dose 3 - Acute Myeloid Leukemia, Acute Lymphoid Leukemia | Phase 1 | Withdrawn | Medigene AG | 2020-07-02 | 2021-10-08 | |
| TCR Modified T Cells MDG1011 in High Risk Myeloid and Lymphoid Neoplasms MDG1011, Investigator Choice therapy - Safety, Tolerability | Phase 1 / Phase 2 | Terminated | Medigene AG | 9 | 2018-03-27 | 2023-02-15 |
| DC Vaccination for Post-remission Therapy in AML WT1/PRAME vaccination - Acute Myeloid Leukemia | Phase 1 / Phase 2 | Completed | Medigene AG | 20 | 2015-03-01 | 2020-07-07 |
| Topical Green Tea Ointment in Treatment of Superficial Skin Cancer Sinecatechins 10%, Placebo - Carcinoma, Basal Cell | Phase 2 / Phase 3 | Completed | Maastricht University Medical Center | 42 | 2014-11-01 | 2016-05-18 |
Leukemia, Myeloid, Acute (2) · Carcinoma, Basal Cell (1) · Carcinoma, Ovarian Epithelial (1) · Hematologic Neoplasms (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Liposarcoma, Myxoid (1) · Lymphoma (1) · Multiple Myeloma (1) · Myelodysplastic Syndromes (1) · Myeloproliferative Disorders (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Primary Myelofibrosis (1) · Sarcoma (1) · Sarcoma, Synovial (1)
green tea extract polyphenone E (1)
Netherlands (2) · Germany (1) · Norway (1) · United States (1)
David Dr. Zhen, MD (1) · Nicole WJ Kelleners-Smeets, MD, PhD (1) · Peter van Balen, MD (1) · Rene Goedkoop, MD (1) · Simone Thomas, PD Dr. med. (1)