3 recruiting, 1 active not recruiting. 3 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 3 |
| Not applicable | 1 | Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients Bevonescein (ALM 488) Infusion - Head and Neck Disorder, Head and Neck Cancer | Phase 2 | Recruiting | Matthew Spector | 40 | 2026-10-18 | 2026-10-19 |
| Window of Opportunity in Preserving Laryngeal Function Trial Toripalimab, Carboplatin, Cisplatin - Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Locally Advanced Laryngeal Squamous Cell Carcinoma | Phase 2 | Recruiting | Matthew Spector | 87 | 2026-04-06 | 2026-10-16 |
| Axoguard HA Plus Nerve Protector to Reduce Post-operative Neck and Shoulder Dysfunction in Patients Undergoing Neck Dissection Spinal Accessory Nerve Protection utilizing Axoguard HA+ - Head and Neck Cancer, Neck Dissection | Not applicable | Active not recruiting | Matthew Spector | 90 | 2025-12-09 | 2026-05-12 |
| Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction Removal of pharyngeal mucosa with decreased perfusion will be performed, SPY-PHI, ICG (Indocyanine Green) - Squamous Cell Carcinoma, Pharyngocutaneous Fistula | Phase 2 | Recruiting | Matthew Spector | 225 | 2025-02-28 | 2026-01-09 |
Head and Neck Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Carcinoma, Squamous Cell (1) · Neoplasm Metastasis (1) · Recurrence (1)
Albumin-Bound Paclitaxel (1) · Carboplatin (1) · Cisplatin (1) · Indocyanine Green (1) · Paclitaxel (1) · Radiotherapy (1) · Radiotherapy, Intensity-Modulated (1) · toripalimab (1)
United States (4)
Daniel Zandberg (1) · Matthew E Spector (1) · Matthew E Spector, MD (1)