2 active not recruiting, 2 recruiting, 1 completed. 5 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Active not recruiting 2, Recruiting 2, Completed 1 |
| Phase 2 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessing PI3K Gamma Inhibition With Azacitidine, Venetoclax and Eganelisib in Patients With Acute Myeloid Leukemia Eganelisib, Azacitidine, Venetoclax - Leukemia, Myeloid, Leukemia | Phase 1 | Recruiting | Jacqueline Garcia, MD | 48 | 2026-04-13 | 2026-08-26 |
| A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax Tagraxofusp, Azacitidine (AZA), Venetoclax - Acute Myeloid Leukaemia (AML), Leukemia | Phase 1 / Phase 2 | Recruiting | Jacqueline Garcia, MD | 31 | 2026-02-02 | 2026-02-05 |
| Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms Navitoclax, Venetoclax, Decitabine - Myeloid Malignancy, Myelodysplastic Syndromes | Phase 1 | Active not recruiting | Jacqueline Garcia, MD | 16 | 2022-07-18 | 2026-01-28 |
| Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN Venetoclax, Fludarabine, Busulfan - Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS) | Phase 1 | Active not recruiting | Jacqueline Garcia, MD | 102 | 2018-10-24 | 2026-05-20 |
| Combination Merestinib and LY2874455 for Patients With Relapsed or Refractory Acute Myeloid Leukemia Merestinib, LY2874455 - Relapsed Adult Acute Myeloid Leukemia, Refractory Adult Acute Myeloid Leukemia | Phase 1 | Completed | Jacqueline Garcia, MD | 16 | 2017-08-10 | 2020-06-30 |
Leukemia, Myeloid, Acute (5) · Leukemia (2) · Myelodysplastic Syndromes (2) · Hematologic Neoplasms (1) · Leukemia, Myeloid (1) · Leukemia, Myelomonocytic, Chronic (1) · Myeloproliferative Disorders (1) · Neoplasm, Residual (1) · Primary Myelofibrosis (1)
venetoclax (4) · Azacitidine (3) · 2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3yl)vinyl)-1H-pyrazol-1-yl)ethanol (1) · Busulfan (1) · Decitabine (1) · IPI-549 (1) · decitabine and cedazuridine drug combination (1) · fludarabine (1) · fludarabine phosphate (1) · merestinib (1) · navitoclax (1) · tagraxofusp (1)
United States (5)
Jacqueline S. Garcia, MD (2) · Jacqueline S Garcia, MD (1)