3 completed, 3 unknown, 1 terminated. 5 Phase 3, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Unknown 3, Completed 2 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM) Obinutuzumab, Cyclophosphamide, Doxorubicin - Non-Hodgkin's Lymphoma | Phase 3 | Completed | Hoffmann-La Roche | 1401 | 2011-07-06 | 2022-08-11 |
| Rituximab and Involved Field Radiotherapy in Early Stage Follicular Lymphoma Rituximab - Lymphoma, Malignant | Phase 2 | Completed | Klaus Herfarth, MD | 85 | 2008-03-01 | 2020-01-06 |
| Primary Rituximab and Maintenance Rituximab - Follicular Lymphoma | Phase 3 | Completed | Lymphoma Study Association | 1217 | 2004-12-01 | 2017-03-13 |
| Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL Rituximab, Cyclophosphamide, Doxorubicin - Lymphoma, Mantle-Cell | Phase 3 | Unknown | European Mantle Cell Lymphoma Network | 360 | 2004-07-01 | 2012-09-10 |
| Induction Chemotherapy (R-CHOP Vs. R-FC) Followed by Interferon Maintenance Versus Rituximab Maintenance in MCL Rituximab, Cyclophosphamide, Doxorubicin - Lymphoma, Mantle-Cell | Phase 3 | Unknown | European Mantle Cell Lymphoma Network | 570 | 2004-01-14 | 2017-03-07 |
| Study With Rituximab-Gemcitabine/Oxaliplatin in Relapsed Indolent Lymphoma Therapy with Rituximab, Gemcitabine and Oxaliplatin - Indolent Lymphoma | Phase 1 / Phase 2 | Terminated | German Low Grade Lymphoma Study Group | 56 | 2003-01-01 | 2015-08-19 |
| Chemotherapy Followed by Radiation Therapy and Peripheral Stem Cell Transplant Compared With Chemotherapy Plus Interferon Alfa in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma filgrastim, recombinant interferon alfa, carmustine - Lymphoma | Phase 3 | Unknown | German Low Grade Lymphoma Study Group | 2000-12-01 | 2013-09-17 |
Lymphoma (3) · Lymphoma, Mantle-Cell (3) · Lymphoma, Follicular (1) · Lymphoma, Non-Hodgkin (1)
Rituximab (6) · Cyclophosphamide (4) · Doxorubicin (3) · Prednisone (3) · Vincristine (3) · Carmustine (2) · Cytarabine (2) · Dexamethasone (2) · Etoposide (2) · Interferon-alpha (2) · Melphalan (2) · R-CHOP protocol (2) · Bendamustine Hydrochloride (1) · Cisplatin (1) · Filgrastim (1)
Germany (5) · France (4) · Belgium (3) · Italy (3) · Australia (2) · Czechia (2) · Denmark (2) · Netherlands (2) · Poland (2) · Spain (2) · Argentina (1) · Brazil (1) · Canada (1) · China (1) · Colombia (1)
Achiel Van Hoof, MD (1) · Alessandro Levis, MD (1) · Gilles A Salles, MD PhD (1) · Hanneke C. Kluin-Nelemans, PhD (1) · J. C. Kluin-Nelemans, MD, PhD (1) · Klaus Herfarth, MD (1) · Martin Dreyling, PhD (1) · Martin Hoffmann, Dr. (1) · Olivier Hermine, PhD (1) · Wolfgang Hiddemann, MD, PhD (1) · Wolfgang Hiddemann, PhD (1)
PMID 20032498, PMID 24687837, PMID 18077791, PMID 21176949, PMID 22873532, PMID 22885164, PMID 25029908, PMID 26022239, PMID 27313086, PMID 28976863, PMID 29856692, PMID 30309758, PMID 30341058, PMID 31053601, PMID 31339826, PMID 31723798, PMID 31804876, PMID 32314038, PMID 34323957, PMID 35194005, PMID 36379880, PMID 36469833, PMID 37957542, PMID 37992261, PMID 38096461, PMID 38459156, PMID 41879719