GenVec: Clinical Trials

8 completed, 1 unknown. 6 Phase 2, 4 Phase 1, 1 Phase 3.

By phase and status

Phase	Trials	Status
Phase 2	6	Completed 6
Phase 1	4	Completed 3, Unknown 1
Phase 3	1	Completed 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Study to Treat Patients Whose Chronic Angina Symptoms Are Not Relieved by Medication and Have an Area of the Heart That Cannot be Treated by Standard Therapies BioBypass® - Moderate to Severe Angina Pectoris	Phase 2	Completed	GenVec	129	2005-04-01	2011-05-13
Study of AdGVPEDF.11D in Neovascular Age-related Macular Degeneration (AMD) AdGVPEDF.11D - Macular Degeneration	Phase 1	Completed	GenVec			2011-05-12
A Study of TNFerade™ Biologic With 5-FU and Radiation Therapy for First-Line Treatment of Unresectable Locally Advanced Pancreatic Cancer TNFerade - Pancreatic Cancer	Phase 3	Completed	GenVec			2012-02-23
TNFerade Biologic to Treat Locally Advanced Prostate Cancer TNFerade™ Biologic - Locally Advanced Prostate Cancer	Phase 1	Unknown	GenVec	20		2012-03-12
TNFerade™ Plus Chemo/Radiation/Surgery for Rectal Cancer TNFerade™ - Rectal Cancer	Phase 2	Completed	GenVec			2012-02-23
TNFerade™ Biologic Plus Radiation for Metastatic Melanoma TNFerade™ - Melanoma	Phase 2	Completed	GenVec			2011-05-12
Study of TNFerade™ Gene Therapy, Radiation, 5-FU and Cisplatin in Esophageal Cancer TNFerade - Esophageal Cancer	Phase 2	Completed	GenVec			2011-05-12
A Study of TNFerade™ Biologic With Concomitant Radiotherapy, Fluorouracil, and Hydroxyurea (TNF-FHX) in Patients With Head and Neck Cancer TNFerade biologic - Head and Neck Cancer, Head and Neck Neoplasms	Phase 1 / Phase 2	Completed	GenVec			2012-02-23
Radiotherapy, Cetuximab, and Injections of TNFerade™ Biologic for Elderly or Frail Patients With Head and Neck Cancer TNFerade biologic - Head and Neck Cancer, Head and Neck Neoplasms	Phase 1 / Phase 2	Completed	GenVec			2012-02-23

Conditions studied

Head and Neck Neoplasms (2)  ·  Neoplasms (2)  ·  Esophageal Neoplasms (1)  ·  Macular Degeneration (1)  ·  Melanoma (1)  ·  Pancreatic Neoplasms (1)  ·  Rectal Neoplasms (1)

Interventions

TNFeraseBiologic (1)

Countries

United States (8)  ·  Denmark (1)  ·  Israel (1)

Top investigators

Dr. Jens Kastrup (1)  ·  Everett Vokes, MD (1)  ·  Everett Vokes,, MD (1)

Results publications

PMID 22520270, PMID 23341531