2 terminated, 1 active not recruiting, 1 recruiting. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Terminated 2, Active not recruiting 1, Recruiting 1 |
| Phase 1 | 2 | Active not recruiting 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL cemacabtagene ansegedleucel, Fludarabine, Cyclophosphamide - Large B-cell Lymphoma | Phase 2 | Recruiting | Allogene Therapeutics | 250 | 2024-06-18 | 2026-10-30 |
| Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy ALLO-647, Fludarabine, Cyclophosphamide - Relapsed/Refractory Large B Cell Lymphoma | Phase 2 | Terminated | Allogene Therapeutics | 2 | 2023-11-01 | 2026-03-02 |
| Safety and Efficacy of ALLO-605 an Anti-BCMA Allogeneic CAR T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma ALLO-605, ALLO-647, Fludarabine - Relapsed/Refractory Multiple Myeloma | Phase 1 / Phase 2 | Terminated | Allogene Therapeutics | 6 | 2021-06-06 | 2024-06-28 |
| Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2) ALLO-501A, ALLO-647, Fludarabine - Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma | Phase 1 / Phase 2 | Active not recruiting | Allogene Therapeutics | 160 | 2020-05-21 | 2026-03-04 |
Lymphoma (2) · Recurrence (2) · Leukemia (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Lymphoma, Large B-Cell, Diffuse (1) · Multiple Myeloma (1) · Neoplasm, Residual (1)
Cyclophosphamide (4) · fludarabine (4) · fludarabine phosphate (1)
United States (4) · Australia (2) · Canada (2) · Belgium (1) · South Korea (1)