3 completed, 1 active not recruiting, 1 unknown. 5 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 3, Active not recruiting 1, Unknown 1 |
| Phase 2 | 2 | Active not recruiting 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ALG.APV-527 First-in-human Study ALG.APV-527 - Solid Tumor | Phase 1 / Phase 2 | Unknown | Aptevo Therapeutics | 56 | 2022-12-23 | 2023-07-07 |
| Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients CD40 agonist mitazalimab in combination with chemotherapy - Metastatic Pancreatic Ductal Adenocarcinoma | Phase 1 / Phase 2 | Active not recruiting | Alligator Bioscience AB | 94 | 2021-09-17 | 2025-10-08 |
| Phase 1 Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of ATOR-1017 ATOR-1017 - Solid Tumor, Neoplasms | Phase 1 | Completed | Alligator Bioscience AB | 27 | 2019-12-03 | 2023-04-24 |
| Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of ATOR-1015 ATOR-1015 - Solid Tumor, Neoplasms | Phase 1 | Completed | Alligator Bioscience AB | 33 | 2019-01-30 | 2022-08-18 |
| ADC-1013 First-in-Human Study ADC-1013 - Neoplasms, Solid Tumors | Phase 1 | Completed | Alligator Bioscience AB | 24 | 2015-04-01 | 2017-03-27 |
Neoplasms (3) · Motor Activity (1) · Pancreatic Neoplasms (1)
mitazalimab (2) · Drug Therapy (1)
Sweden (3) · Denmark (2) · Belgium (1) · France (1) · Spain (1) · United Kingdom (1) · United States (1)
Dorte Nielsen, MD, PhD (1) · Gustav Ullenhag, Dr (1) · Jean-Luc van Laethem, Prof. MD (1) · Jeffrey Yachnin, Dr (1) · Malin Carlsson, MD (1) · Sumeet Ambarkhane, MD (1)