3 completed, 1 active not recruiting, 1 not yet recruiting, 1 recruiting. 4 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Active not recruiting 1 |
| Phase 2 | 3 | Active not recruiting 1, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow mitazalimab: new trials by email Literature Review of mitazalimab trials Research Report on mitazalimab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing Mitazalimab in Combination With Standard Chemotherapy in Immunotherapy Resistant Advanced Biliary Tract Cancers mFOLFOX regimen, Mitazalimab - Biliary Tract Cancer (BTC) | Phase 2 / Phase 3 | Not yet recruiting | UNICANCER | 160 | 2026-07-01 | 2026-02-27 |
| Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer Odetiglucan, Mitazalimab - Pancreatic Ductal Adenocarcinoma | Phase 2 | Recruiting | University of Pennsylvania | 100 | 2025-11-25 | 2026-06-10 |
| Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients CD40 agonist mitazalimab in combination with chemotherapy - Metastatic Pancreatic Ductal Adenocarcinoma | Phase 1 / Phase 2 | Active not recruiting | Alligator Bioscience AB | 94 | 2021-09-17 | 2025-10-08 |
| MesoPher/Mitazalimab-combination Therapy in Metastatic Pancreatic Disease (REACtiVe-2 Trial) MesoPher, Mitazalimab - Metastatic Pancreatic Cancer | Phase 1 | Completed | Joachim Aerts, MD PhD | 22 | 2021-08-30 | 2023-10-12 |
| A Study of Safety, Pharmacokinetics and Pharmacodynamics of JNJ-64457107 in Participants With Advanced Stage Tumors JNJ-64457107 - Advanced Solid Neoplasms | Phase 1 | Completed | Janssen Research & Development, LLC | 95 | 2016-09-21 | 2022-10-06 |
| ADC-1013 First-in-Human Study ADC-1013 - Neoplasms, Solid Tumors | Phase 1 | Completed | Alligator Bioscience AB | 24 | 2015-04-01 | 2017-03-27 |
Pancreatic Neoplasms (2) · Biliary Tract Neoplasms (1) · Motor Activity (1) · Neoplasms (1)
Alligator Bioscience AB (2) · Janssen Research & Development, LLC (1) · Joachim Aerts, MD PhD (1) · UNICANCER (1) · University of Pennsylvania (1)
France (2) · Spain (2) · Belgium (1) · Denmark (1) · Israel (1) · Netherlands (1) · Sweden (1) · United Kingdom (1) · United States (1)
Dorte Nielsen, MD, PhD (1) · Ferry Eskens, MD, PhD (1) · Jean-Luc van Laethem, Prof. MD (1)
PMID 36538259, PMID 37830579, PMID 38834087, PMID 41061701
2016 (1)