5 completed, 1 recruiting. 2 Phase 1, 2 Phase 2, 1 Early Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 2 | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow X842: new trials by email Literature Review of X842 trials Research Report on X842
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate Linaprazan glurate, Placebo - Pharmacokinetics, Cardiodynamic ECG | Phase 1 | Recruiting | Cinclus Pharma Holding AB | 121 | 2022-07-13 | 2026-06-17 |
| A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole X842, X842 Dummy, Lansoprazole - Erosive Esophagitis | Phase 2 | Completed | Cinclus Pharma Holding AB | 248 | 2021-08-11 | 2026-07-01 |
| The Phase III Clinical Trial of X842 Capsules for Reflux Esophagitis X842, X842 Placebo, Lansoprazole - Reflux Esophagitis | Phase 3 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 380 | 2021-06-24 | 2025-07-23 |
| Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis X842, X842 Placebo, Lansoprazole - Reflux Esophagitis | Phase 2 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 90 | 2020-01-21 | 2025-07-17 |
| Single-dose and Multiple-dose X842 Phase 1 Study Single ascending dose of X842, Multiple ascending dose of X842, Food Effect - Healthy Volunteers | Phase 1 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 80 | 2018-10-23 | 2020-03-06 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of X842 in Human: A Single/Multiple Ascending Dose Study Single ascending dose of X842, Multiple ascending dose of X842, Losec - Healthy Volunteers | Early Phase 1 | Completed | Cinclus Pharma Holding AB | 39 | 2017-02-21 | 2026-06-17 |
Gastroesophageal Reflux (4) · Esophagitis (2) · Esophagitis, Peptic (2)
Cinclus Pharma Holding AB (3) · Jiangsu Sinorda Biomedicine Co., Ltd (3)
China (3) · Sweden (2) · Bulgaria (1) · Czechia (1) · Georgia (1) · Hungary (1) · Poland (1) · Serbia (1) · Ukraine (1) · United States (1)
Pingsheng Hu, Ph.D (3) · Cornelia Lif-Tiberg, MD (1) · Erik Rein-Hedin, MD (1)