4 completed, 2 recruiting, 1 not yet recruiting. 5 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 4, Not yet recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Wide Local Excision: new trials by email Literature Review of Wide Local Excision trials Research Report on Wide Local Excision
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information Biospecimen Collection, Chest Radiography, Computed Tomography - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 2 | Recruiting | Children's Oncology Group | 51 | 2027-05-15 | 2026-09-24 |
| Trial Comparing CPDMA Versus Standard Breadloafing in WLE Specimens of Stage 1-II Cutaneous Melanoma Wide Local Excision - Cutaneous Melanoma, Stage II, Cutaneous Melanoma | Not applicable | Not yet recruiting | University of Nebraska | 282 | 2026-12-24 | 2026-10-09 |
| Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma Adjuvant Therapy, Comprehensive Geriatric Assessment, Computed Tomography - Cutaneous Melanoma | Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 428 | 2026-04-17 | 2026-09-24 |
| A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia Frozen-Section Directed Excision, Wide Local Excision - Vulvar Neoplasm, Dysplasia Vulvar | Not applicable | Completed | Wake Forest University Health Sciences | 17 | 2023-11-07 | 2026-10-29 |
| Treatment of Dermatofibrosarcoma Protuberans in Patients 10 Years and Younger MOHS micrographic surgery, Wide local excision - Dermatofibrosarcoma Protuberans | Not applicable | Completed | Mayo Clinic | 7 | 2018-07-01 | 2020-08-05 |
| Study of 1cm Versus 2cm Margins for the Surgical Treatment of cT2N0M0 Melanoma Wide Local Excision - Malignant Melanoma | Not applicable | Completed | University of Kansas Medical Center | 15 | 2017-01-30 | 2021-05-03 |
| A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall proton radiation, surgery (wide local excision; limb preservation surgery) - Soft Tissue Sarcoma | Not applicable | Completed | Loma Linda University | 7 | 2013-02-27 | 2023-08-23 |
Melanoma (4) · Dermatofibrosarcoma (1) · Sarcoma (1) · Vulvar Neoplasms (1)
Children's Oncology Group (1) · ECOG-ACRIN Cancer Research Group (1) · Loma Linda University (1) · Mayo Clinic (1) · University of Kansas Medical Center (1) · University of Nebraska (1) · Wake Forest University Health Sciences (1)
United States (7)
Brittani K Seynnaeve (1) · Gary Yang, MD (1) · Joshua Mammen (1) · Joshua Mammen, MD (1) · Randall K Roenigk (1) · Robert W Naumann, MD (1) · Yana Najjar (1)
P30CA012197 (1), U10CA180820 (1), U10CA180886 (1)