7 completed. 3 Phase 3, 2 Phase 1, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Vitrase: new trials by email Literature Review of Vitrase trials Research Report on Vitrase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hyaluronidase Via LADD Scleroderma-induced Microstomia Hyaluronidase, CO2 laser - Microstomia, Scleroderma | Early Phase 1 | Completed | University of Nebraska | 3 | 2024-03-01 | 2026-04-15 |
| Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment Vitrase - Vitreous Detachment, Diabetic Retinopathy | Phase 2 | Completed | Bausch & Lomb Incorporated | 10 | 2005-07-01 | 2013-03-15 |
| Evaluation of Vitrase as a Spreading Agent Vitrase - Pain | Phase 3 | Completed | Bausch & Lomb Incorporated | 108 | 2004-10-01 | 2013-03-14 |
| Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase) Vitrase - Drug Hypersensitivity | Phase 1 | Completed | Bausch & Lomb Incorporated | 65 | 2004-07-01 | 2013-03-18 |
| Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase) Vitrase - Drug Hypersensitivity | Phase 1 | Completed | Bausch & Lomb Incorporated | 65 | 2004-03-01 | 2013-03-14 |
| Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage Placebo, Vitrase - Vitreous Hemorrhage, Diabetic Retinopathy | Phase 3 | Completed | Bausch & Lomb Incorporated | 510 | 1999-06-01 | 2013-03-15 |
| Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage Vitrase - Vitreous Hemorrhage, Diabetic Retinopathy | Phase 3 | Completed | Bausch & Lomb Incorporated | 750 | 1998-11-01 | 2013-03-15 |
Diabetic Retinopathy (3) · Drug Hypersensitivity (2) · Vitreous Hemorrhage (2) · Microstomia (1) · Pain (1) · Scleroderma, Diffuse (1) · Vitreous Detachment (1)
Bausch & Lomb Incorporated (6) · University of Nebraska (1)
United States (6) · Australia (1) · Brazil (1) · Canada (1) · Hungary (1) · Italy (1) · Mexico (1) · Netherlands (1) · Poland (1) · South Africa (1) · Spain (1) · United Kingdom (1)
Lisa R Grillone, PhD (5) · Jon Williams, PhD (1) · Sarah L Lonowski, MD (1)