10 terminated. 10 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Terminated 10 |
| Phase 1 | 2 | Terminated 2 |
Follow Vismodegib: new trials by email Literature Review of Vismodegib trials Research Report on Vismodegib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| To Assess The Efficacy And Safety Of Vismodegib And Radiotherapy In Advanced Basal Cell Carcinoma Vismodegib, Radiotherapy - Carcinoma, Basal Cell | Phase 2 | Terminated | Istituto Clinico Humanitas | 14 | 2016-10-01 | 2020-01-29 |
| Vismodegib in Treating Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease Laboratory Biomarker Analysis, Vismodegib - Chronic Graft Versus Host Disease | Phase 2 | Terminated | National Cancer Institute (NCI) | 6 | 2015-09-08 | 2021-07-19 |
| Vismodegib in Basal Cell Carcinomas (BCC) Chemoprevention Vismodegib, Placebo - Basal Cell Carcinomas | Phase 2 | Terminated | University of Arizona | 9 | 2014-02-17 | 2019-08-14 |
| A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma Placebo, Vismodegib - Basal Cell Carcinoma | Phase 2 | Terminated | Hoffmann-La Roche | 18 | 2014-01-23 | 2017-05-08 |
| A Study of Vismodegib in Patients With Relapsed/Refractory Acute Myelogenous Leukemia and Relapsed Refractory High-Risk Myelodysplastic Syndrome cytarabine, vismodegib - Myelodysplastic Syndromes, Myelogenous Leukemia, Acute | Phase 2 | Terminated | Hoffmann-La Roche | 38 | 2013-09-01 | 2015-12-15 |
| Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma Vismodegib - Pontine Glioma | Phase 2 | Terminated | Giselle Sholler | 9 | 2013-05-01 | 2024-08-06 |
| Phase II Study of Vismodegib in Patients With Refractory or Relapsed B-cell Lymphoma or Chronic Lymphocytic Leukemia Vismodegib - Diffuse Large B-cell Lymphoma, Indolent Non-hodgkin Lymphoma | Phase 2 | Terminated | The Lymphoma Academic Research Organisation | 31 | 2013-02-01 | 2017-03-13 |
| Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway vismodegib, Temozolomide - Histologically Confirmed Medulloblastoma, Activation of the Sonic Hedgehog (SHH) Pathway | Phase 1 / Phase 2 | Terminated | Centre Leon Berard | 24 | 2012-06-01 | 2019-05-21 |
| Hedgehog Inhibition for Pancreatic Ductal Adenocarcinoma (PDAC) in the Preoperative Setting (HIPPoS) GDC-0449 - Pancreatic Ductal Adenocarcinoma | Phase 2 | Terminated | Lisa Bax | 3 | 2011-02-01 | 2014-01-08 |
| Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer Goserelin Acetate, Laboratory Biomarker Analysis, Leuprolide Acetate - Prostate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v7 | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 10 | 2010-07-09 | 2019-02-28 |
Carcinoma, Basal Cell (3) · Adenocarcinoma (1) · Bronchiolitis Obliterans Syndrome (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myeloid (1) · Lymphoma, Large B-Cell, Diffuse (1) · Medulloblastoma (1) · Microphthalmia, Isolated, with Coloboma 5 (1) · Myelodysplastic Syndromes (1) · Neoplasms (1) · Prostatic Neoplasms (1) · Recurrence (1)
Hoffmann-La Roche (2) · National Cancer Institute (NCI) (2) · Centre Leon Berard (1) · Giselle Sholler (1) · Istituto Clinico Humanitas (1) · Lisa Bax (1) · The Lymphoma Academic Research Organisation (1) · University of Arizona (1)
United States (6) · France (2) · Italy (2) · United Kingdom (2) · Canada (1) · Germany (1) · Switzerland (1)
Albert Cornelius, MD (1) · Armando Santoro, MD (1) · Christopher Logothetis (1) · Clara Curiel-Lewandroski (1) · Daniel R Couriel (1) · David Tuveson, MD PhD (1) · Giselle Sholler, MD (1)
N01CM00039 (1), N01CM62202 (1), P30CA016672 (1), P30CA042014 (1), U01CA062461 (1), U01CA062491 (1)