3 completed, 1 recruiting. 2 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow vaborbactam: new trials by email Literature Review of vaborbactam trials Research Report on vaborbactam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess How Vaborem® is Taking up in the Body and Tolerated in Paediatric Patients With Gram Negative Infections, Including But Not Restricted to Complicated Urinary Tract Infections Meropenem plus vaborbactam - Gram Negative Infections | Phase 2 | Recruiting | Menarini Group | 44 | 2025-02-18 | 2026-10-07 |
| Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections Vabomere - Bacterial Infections | Phase 1 | Completed | Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) | 39 | 2016-07-01 | 2026-08-17 |
| Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP Meropenem-Vaborbactam, Piperacillin-Tazobactam, Levofloxacin - Urinary Tract Infection Complicated, Acute Pyelonephritis | Phase 3 | Completed | Melinta Therapeutics, Inc. | 550 | 2014-11-20 | 2018-06-11 |
| Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults Vabomere, Best Available Therapy - Urinary Tract Infection Complicated, Acute Pyelonephritis | Phase 3 | Completed | Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.) | 77 | 2014-07-01 | 2019-03-04 |
Bacteremia (1) · Bacterial Infections (1) · Intraabdominal Infections (1)
Melinta Therapeutics, Inc. (1) · Menarini Group (1) · Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.) (1) · Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) (1)
Italy (3) · United States (3) · Brazil (2) · Czechia (2) · Greece (2) · Poland (2) · Spain (2) · Argentina (1) · Belarus (1) · Bulgaria (1) · Colombia (1) · France (1) · Hungary (1) · Israel (1) · Peru (1)
Karen Fusaro (2) · Keith Kaye (2)
PMID 29486041, PMID 30270406, PMID 33565042, PMID 39964222
2016 (1)