3 completed, 2 unknown, 1 terminated. 2 Not applicable, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 1 | Unknown 1 |
Follow tramiprosate: new trials by email Literature Review of tramiprosate trials Research Report on tramiprosate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Unravelling the Effects of Nicotinamide/Pyrroloquinolone Quinone /Citicoline/Homotaurine Fixed Combination on Contrast Sensitivity, Quality of Life, and Reading Performance in Glaucoma Citicoline 500 MG (Optigen) for 4 months, citicoline 500 mg + nicotinamide 54 mg + PQQ 5 mg + Homotaurine 50 mg fixed combination tablet (Neuprozin mito) - Glaucoma | Not applicable | Completed | Università degli Studi 'G. d'Annunzio' Chieti e Pescara | 44 | 2025-11-01 | 2026-10-06 |
| Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in Glaucoma Citicoline 500 mg plus Homotaurine 50 mg plus Pyrroloquinoline quinone (Neuprozin Mito® ) - Glaucoma, Neuroprotection | Phase 3 | Completed | Fondazione IRCCS Policlinico San Matteo di Pavia | 40 | 2024-01-27 | 2025-05-01 |
| The Effects of Cannabidiol and Homotaurine in Patients With Mild Cognitive Impairment Cannabidiol Oil, Homotaurine - Mild Cognitive Impairment | Phase 4 | Unknown | Aristotle University Of Thessaloniki | 90 | 2021-04-01 | 2021-08-26 |
| Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy curcumin, homotaurine, vitamin D3, control - Diabetic Retinopathy | Completed | University of Molise | 25 | 2019-09-16 | 2020-05-07 | |
| Effect of Citicoline/Homotaurine on PERG in Primary Open Angle Glaucoma Citicoline 500 mg plus Homotaurine 50 mg - Glaucoma | Not applicable | Terminated | Fondazione IRCCS Policlinico San Matteo di Pavia | 63 | 2018-01-25 | 2025-05-01 |
| Open-Label Extension of the Phase III Study With Tramiprosate (3APS) in Patients With Mild to Moderate Alzheimer's Disease Tramiprosate (3APS) - Alzheimer's Disease | Phase 3 | Unknown | Bellus Health Inc. - a GSK company | 650 | 2006-05-01 | 2007-07-16 |
Glaucoma (3) · Alzheimer Disease (1) · Cognitive Dysfunction (1) · Diabetic Retinopathy (1) · Ornithine Carbamoyltransferase Deficiency Disease (1) · Psychological Well-Being (1)
Fondazione IRCCS Policlinico San Matteo di Pavia (2) · Aristotle University Of Thessaloniki (1) · Bellus Health Inc. - a GSK company (1) · University of Molise (1) · Università degli Studi 'G. d'Annunzio' Chieti e Pescara (1)
Italy (4) · Greece (1) · United States (1)
Ciro Costagliola, Full Professor (1) · Ciro Costagliola, MD (1)
PMID 10990036, PMID 19660572, PMID 20580421, PMID 21921569, PMID 22346117, PMID 22455417, PMID 23365490, PMID 24198445, PMID 24379919, PMID 24680929, PMID 25258680, PMID 26137497, PMID 26173446, PMID 26676667, PMID 27618014, PMID 30951889, PMID 33633656