25 completed, 2 terminated. 27 Phase 1, 2 Phase 2.
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All 27 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Bioequivalence of Two Different Oral Solutions Tipranavir Administered in Combination With Ritonavir to Healthy Volunteers
Tipranavir, Ritonavir - Healthy | Phase 1 | Completed | 32 | 2008-04-01 | 2014-09-19 |
Effects of Steady State Tipranavir/Ritonavir or Darunavir/Ritonavir or Ritonavir on Platelet Function, Coagulation and Fibrinolysis Biomarkers in Healthy Subjects
Tipranavir, Ritonavir, Darunavir - Healthy | Phase 1 | Completed | 52 | 2007-08-01 | 2014-09-29 |
Pharmacokinetic (PK) Study of Single-dose Rosuvastatin and Tipranavir/Ritonavir in Healthy Subjects
Tipranavir/Ritonavir, Rosuvastatin - HIV Infections | Phase 1 | Completed | 29 | 2007-02-01 | 2016-02-04 |
Pharmacokinetic Interaction Study of Steady-state Tipranavir/Ritonavir (TPV/r) With Single-dose Valaciclovir (VAL) in Healthy Volunteers
Tipranavir, Ritonavir, Valaciclovir - Healthy | Phase 1 | Completed | 29 | 2007-02-01 | 2014-08-27 |
Effect of Steady State TPV/r on Intracellular Concentrations of Zidovudine and Carbovir for Patients With HIV
Tipranavir capsules, Ritonavir capsules - HIV Infections | Phase 1 / Phase 2 | Terminated | 3 | 2006-08-01 | 2014-09-01 |
Effects of Steady-state Efavirenz 600 mg QD (Sustiva®) on Tipranavir Concentration at Steady-state in Healthy Adult Volunteers
Tipranavir, Ritonavir, Efavirenz - Healthy | Phase 1 | Completed | 34 | 2006-04-01 | 2014-08-27 |
Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers
Tipranavir capsule, Tipranavir solution, Ritonavir capsule - Healthy | Phase 1 | Completed | 34 | 2006-01-01 | 2014-09-18 |
Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment
Tipranavir, Ritonavir, Pegylated interferon - Hepatic Insufficiency | Phase 1 | Completed | 36 | 2006-01-01 | 2025-01-22 |
Pharmacokinetic of Tadalafil Co-administered With Tipranavir/Ritonavir to Healthy Male Volunteers
Tadalafil, Tipranavir, Ritonavir - Healthy | Phase 1 | Completed | 17 | 2005-12-01 | 2014-10-01 |
Effects of TPV/r on the Pharmacokinetics of Carbamazepine in Healthy Adult Volunteers
Carbamazepine, Tipranavir, Ritonavir - Healthy | Phase 1 | Completed | 28 | 2005-11-01 | 2014-10-01 |
Study to Determine the Effects of Multiple-dose Omeprazole on the Single-dose Pharmacokinetics of Tipranavir (TPV) Coadministered With Ritonavir (RTV) in Healthy Adult Volunteers
Tipranavir (TPV), Ritonavir, Omeprazole - Healthy | Phase 1 | Completed | 15 | 2005-11-01 | 2014-10-01 |
Pharmacokinetic Interaction Between Tipranavir and BILR 355 BS Plus Ritonavir in Healthy Male Volunteers
BILR 355 BS, Tipranavir, Low dose of ritonavir - Healthy | Phase 1 | Completed | 34 | 2005-02-01 | 2014-10-06 |
Pharmacokinetic Study in Healthy Adult Volunteers to Assess the Interactions Between Steady-State Tipranavir and Atazanavir in the Presence of Ritonavir
Tipranavir, Ritonavir, Atazanavir - Healthy | Phase 1 | Completed | 21 | 2005-01-01 | 2014-10-01 |
Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIV
Nevirapine, Efavirenz, Indinavir/ritonavir - HIV Infections | Phase 1 | Completed | 675 | 2005-01-01 | 2019-12-04 |
Study of Tipranavir and Ritonavir on the Pharmacokinetic Characteristics of Methadone Administered in Healthy Volunteers
Tipranavir, Ritonavir, Methadone - Healthy | Phase 1 | Completed | 15 | 2005-01-01 | 2014-09-19 |
Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency
Tipranavir (TPV), Ritonavir (r) - Hepatic Insufficiency | Phase 1 | Completed | 24 | 2003-10-01 | 2025-01-23 |
Bioavailability of Tipranavir/Ritonavir Paediatric Solution Compared to Tipranavir/Ritonavir Capsules in Healthy Female and Male Subjects
Tipranavir oral solution, Tipranavir capsules, Ritonavir oral solution - Healthy | Phase 1 | Completed | 30 | 2003-10-01 | 2014-09-29 |
Effects of Single-dose and Steady-state TPV/r on the Steady-state Pharmacokinetics of Clarithromycin and a Preliminary Assessment of the Effects of a Standard High-fat Test Meal on the Steady-state Pharmacokinetics of Tipranavir
Tipranavir, Ritonavir, Clarithromycin - Healthy | Phase 1 | Completed | 24 | 2003-08-01 | 2014-09-29 |
Effects of Steady-state TPV/RTV on the Single-dose Pharmacokinetics of Rifabutin and the Effects of Single-dose Rifabutin on the Steady-state Pharmacokinetics of TPV in Healthy Adult Volunteers
Tipranavir, Ritonavir, Rifabutin - Healthy | Phase 1 | Completed | 24 | 2003-08-01 | 2014-09-29 |
Pharmacokinetics of Atorvastatin With Tipranavir/Ritonavir and the Effect of Antacid on the Pharmacokinetics of Single-Dose Tipranavir/Ritonavir in Healthy Volunteers
Tipranavir, Ritonavir, Atorvastatin - Healthy | Phase 1 | Completed | 23 | 2003-07-01 | 2014-09-19 |
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Conditions studied
HIV Infections (4) · Hepatic Insufficiency (2)
Sponsors
Boehringer Ingelheim (25) · Germans Trias i Pujol Hospital (1) · Johns Hopkins University (1)
Countries
Spain (1) · United States (1)
Top investigators
Bonaventura Clotet, MD, PhD (1) · Paul Pham, PharmD (1)
Results publications
PMID 23494984
NIH funding
2004 (1)