6 completed. 6 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 2 |
Follow TH 302: new trials by email Literature Review of TH 302 trials Research Report on TH 302
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Safety and the Efficacy of the Combination of TH-302 and Sunitinib in Neuroendocrine Pancreatic Tumours TH-302 + Sunitinib - Neuroendocrine Tumors, Pancreatic Neoplasms | Phase 2 | Completed | Grupo Espanol de Tumores Neuroendocrinos | 17 | 2015-05-11 | 2020-07-27 |
| TH-302 in Combination With Bevacizumab for Glioblastoma Bevacizumab, TH-302 - Glioblastoma | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 35 | 2015-05-01 | 2020-04-10 |
| Safety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following Bevacizumab TH-302 preoperative, Placebo, TH-302 (escalating) with bevacizumab 10mg/kg - HIGH GRADE GLIOMA | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 28 | 2011-06-01 | 2019-07-24 |
| Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic Adenocarcinoma Gemzar (Gemcitabine), TH-302 - Pancreatic Adenocarcinoma | Phase 2 | Completed | ImmunoGenesis | 214 | 2010-06-01 | 2025-05-11 |
| Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors TH-302 - Non-Small Cell Lung Cancer, Prostate Cancer | Phase 1 / Phase 2 | Completed | Threshold Pharmaceuticals | 71 | 2008-08-01 | 2015-05-07 |
| Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma TH-302 - Soft Tissue Sarcoma | Phase 1 / Phase 2 | Completed | ImmunoGenesis | 107 | 2008-08-01 | 2025-05-13 |
Pancreatic Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (1) · Glioblastoma (1) · Glioma (1) · Hypoxia (1) · Neuroectodermal Tumors, Primitive (1) · Neuroendocrine Tumors (1) · Prostatic Neoplasms (1) · Sarcoma (1)
ImmunoGenesis (2) · The University of Texas Health Science Center at San Antonio (2) · Grupo Espanol de Tumores Neuroendocrinos (1) · Threshold Pharmaceuticals (1)
United States (5) · Spain (1)
Mitesh Borad, MD (2) · Andrew Brenner, MD (1) · Andrew Brenner, MD, (1) · Enrique Grande, MD (1) · Jeffrey R Infante, MD (1) · Kristen Ganjoo, MD (1) · Shantan Reddy, MD (1)
2014 (1)