Talimogene laherparepvec (T-Vec): Clinical Trials

3 trials of Talimogene laherparepvec (T-Vec), newest first

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1 active not recruiting, 1 completed, 1 withdrawn. 3 Phase 2, 1 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 23Active not recruiting 1, Completed 1, Withdrawn 1
Phase 11Completed 1

Follow Talimogene laherparepvec (T-Vec): new trials by email Literature Review of Talimogene laherparepvec (T-Vec) trials Research Report on Talimogene laherparepvec (T-Vec)

Trials (filtered) newest first · largest first

All 3 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Neoadjuvant Use of Talimogene Laherparepvec and BRAF/MEK Inhibitor for Advanced Nodal BRAF Mutant Melanoma
Talimogene laherparepvec (T-Vec), Dabrafenib (BRAF Inhibitor), Trametinib (MEK Inhibitor) - Melanoma (Skin), Melanoma Stage IIIb-IVM1a
Phase 2WithdrawnTriHealth Inc.2019-06-242020-10-19
TITAN (Tumoural Injection of T-VEC and Isolated Limb Perfusion)
Talimogene laherparepvec (T-VEC) - Melanoma and Sarcoma
Phase 1 / Phase 2CompletedRoyal Marsden NHS Foundation Trust152018-06-262021-08-18
A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Talimogene Laherparepvec (T-VEC), Pembrolizumab - Sarcoma, Epithelioid Sarcoma
Phase 2Active not recruitingMemorial Sloan Kettering Cancer Center412017-03-032026-07-17

Conditions studied

Melanoma (2)  ·  Sarcoma (2)  ·  Neoplasm Metastasis (1)  ·  Skin Neoplasms (1)

Sponsors

Memorial Sloan Kettering Cancer Center (1)  ·  Royal Marsden NHS Foundation Trust (1)  ·  TriHealth Inc. (1)

Countries

United States (2)  ·  United Kingdom (1)

Top investigators

Andrew Hayes (1)  ·  Ciara Kelly, MBBCh BAO (1)

Results publications

PMID 31971541, PMID 34132224, PMID 35115306