11 completed. 11 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 11 |
Follow Suzetrigine: new trials by email Literature Review of Suzetrigine trials Research Report on Suzetrigine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Efavirenz on the Pharmacokinetics of Suzetrigine in Healthy Participants Suzetrigine, Efavirenz - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 18 | 2026-05-07 | 2026-08-18 |
| Evaluation of the Excretion of Suzetrigine Into Breast Milk in Healthy Lactating Female Participants Suzetrigine - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 13 | 2026-02-13 | 2026-09-09 |
| Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female Participants Suzetrigine, DRSP/EE, NGM/EE - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 50 | 2025-02-25 | 2025-05-29 |
| A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine Suzetrigine - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 48 | 2024-03-28 | 2024-07-19 |
| A Study to Evaluate the Effect of Food on the Pharmacokinetics of VX-548 VX-548 - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 73 | 2023-05-03 | 2024-03-20 |
| A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy Participants VX-548, Moxifloxacin, Moxifloxacin Placebo - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 72 | 2023-04-12 | 2024-03-20 |
| Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment VX-548 - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 38 | 2023-02-27 | 2024-04-29 |
| Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy Participants VX-548, Omeprazole, Rifampin - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 31 | 2022-12-15 | 2024-03-20 |
| Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment VX-548 - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 36 | 2022-10-14 | 2024-03-20 |
| A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin VX-548, Midazolam, Digoxin - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 37 | 2022-09-22 | 2024-03-20 |
| A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation of VX-548 VX-548 - Pain | Phase 1 | Completed | Vertex Pharmaceuticals Incorporated | 24 | 2022-07-13 | 2024-03-20 |
Pain (11)
Vertex Pharmaceuticals Incorporated (11)
United States (10) · Australia (1)