12 completed, 2 terminated, 2 unknown. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 12, Terminated 2, Unknown 2 |
Follow Simulect: new trials by email Literature Review of Simulect trials Research Report on Simulect
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major Busulfan, Cyclophosphamide, Fludarabine - Thalassemia Major | Phase 4 | Unknown | First Affiliated Hospital of Guangxi Medical University | 30 | 2017-04-01 | 2017-05-31 |
| Basiliximab vs Low-dose Thymoglobulin Induction Therapy in Low Risk Kidney Transplant Patients Basiliximab, Thymoglobulin - Kidney Transplant Rejection, Kidney Transplant; Complications | Phase 4 | Completed | Coordinación de Investigación en Salud, Mexico | 100 | 2016-12-01 | 2019-11-15 |
| Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients sirolimus, tacrolimus, mycophenolate - Disorder Related to Renal Transplantation, Cytomegalovirus Infections | Phase 4 | Completed | Associação Médico Espírita de Botucatu | 48 | 2014-01-01 | 2016-02-17 |
| Simulect Versus ATG in Sensitized Renal Transplant Patient Simulect, ATG Fresenius - Renal Transplant Rejection | Phase 4 | Completed | University Hospital, Toulouse | 60 | 2013-09-01 | 2026-04-08 |
| A Study Looking at Diabetes in Kidney Transplant Recipients Receiving Immunosuppressive Regimen With or Without Steroids Advagraf, Mycophenolate Mofetil, Simulect - Kidney Transplantation | Phase 4 | Completed | Astellas Pharma Inc | 1166 | 2011-01-22 | 2024-11-01 |
| Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment ATG-F, Simulect - Glomerulonephritis, IgAN | Phase 4 | Terminated | Centre Hospitalier Universitaire de Saint Etienne | 117 | 2011-01-08 | 2021-01-20 |
| Safety and Efficacy of Basiliximab, Delayed Dose Tacrolimus Plus ECMPA (Enteric Coated Mycophenolic Acid) Following Liver Transplantation Basiliximab, Tacrolimus, Mycophenolic Acid - Liver Transplantation | Phase 4 | Completed | University of California, Los Angeles | 59 | 2011-01-01 | 2022-09-29 |
| Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients Everolimus, Tacrolimus (FK506), Basiliximab - Chronic Renal Failure | Phase 4 | Completed | Novartis Pharmaceuticals | 36 | 2009-12-01 | 2014-08-15 |
| Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior Program Basiliximab, Enteric Coated Mycophenolic Acid (MPA), RAD001 - Renal Transplantation | Phase 4 | Terminated | Novartis Pharmaceuticals | 207 | 2009-07-01 | 2014-06-06 |
| Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation cyclosporine, Everolimus - Renal Transplantation | Phase 4 | Unknown | University Hospital, Antwerp | 152 | 2008-10-01 | 2009-05-18 |
| Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal Transplantation Basiliximab, Tacrolimus, MMF, Prednisolon, Basiliximab, Tacrolimus, MMF, Tacrolimus, MMF, rATG - Disorder Related to Renal Transplantation | Phase 4 | Completed | University Hospital Freiburg | 600 | 2008-06-01 | 2014-10-01 |
| A Study in Kidney Transplant Subjects to Investigate the Optimal Suppression of Immunity to Help Prevent Kidney Rejection Prograf®, Advagraf®, Mycophenolate Mofetil - Kidney Transplantation | Phase 4 | Completed | Astellas Pharma Inc | 1252 | 2008-05-14 | 2024-11-01 |
| Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients everolimus, cyclosporine A, Enteric Coated Mycophenolate Sodium (EC-MPS) - Renal Function | Phase 4 | Completed | Novartis Pharmaceuticals | 204 | 2008-03-01 | 2014-08-13 |
| Steroid Free Immunosuppression in Liver Transplantation Steroids, Basiliximab, Tacrolimus - Liver Cirrhosis, Liver Transplant Disorder | Phase 4 | Completed | Thomas Jefferson University | 40 | 2006-02-01 | 2012-11-19 |
| Safety and Efficacy of Basiliximab in Calcineurin Inhibitor Intolerant Long-term Kidney Transplant Recipients Treated With Mycophenolic Acid and Steroids basiliximab, MMF/EC-MPS, Corticosteroids - Kidney Transplantation, Adverse Effects | Phase 4 | Completed | Novartis | 7 | 2006-01-01 | 2017-03-29 |
| Safety/Efficacy of Induction Agents With Tacrolimus, MMF, and Rapid Steroid Withdrawal in Renal Transplant Recipients basiliximab, rabbit anti-thymocyte globulin, tacrolimus - Kidney Transplantation | Phase 4 | Completed | Astellas Pharma Inc | 501 | 2005-05-01 | 2011-08-11 |
Cytomegalovirus Infections (1) · Diabetes Mellitus (1) · Glomerulonephritis (1) · Kidney Failure, Chronic (1) · Liver Cirrhosis (1) · Neoplasms (1) · Renal Insufficiency (1) · beta-Thalassemia (1)
Astellas Pharma Inc (3) · Novartis Pharmaceuticals (3) · Associação Médico Espírita de Botucatu (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Coordinación de Investigación en Salud, Mexico (1) · First Affiliated Hospital of Guangxi Medical University (1) · Novartis (1) · Thomas Jefferson University (1) · University Hospital Freiburg (1) · University Hospital, Antwerp (1) · University Hospital, Toulouse (1) · University of California, Los Angeles (1)
France (4) · Germany (4) · Belgium (3) · Norway (3) · Sweden (3) · Switzerland (3) · United States (3) · Czechia (2) · Hungary (2) · Italy (2) · Mexico (2) · Netherlands (2) · Poland (2) · Portugal (2) · Romania (2)
Carlo Gerardo B Ramirez, M.D. (1) · Christian Hugo, Prof. Dr. (1) · Fady M Kaldas, MD (1) · Gustavo Martinez-Mier, MD (1) · Jean-Louis Bosmans, MD/PhD (1) · Nassim Kamar, MD PhD (1) · Oliver Thomusch, Prof. Dr. (1) · Ulrich Hopt, Prof.Dr.Dr. (1) · Yongrong Lai, MD (1)
PMID 16699456, PMID 17093248, PMID 22850297, PMID 27547871, PMID 27871759, PMID 29149958, PMID 31029086, PMID 31536556, PMID 32775820, PMID 33277746, PMID 37391381, PMID 39382091
2008 (1), 2009 (1)