4 completed, 2 unknown, 1 recruiting, 1 terminated. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 4, Unknown 2, Recruiting 1, Terminated 1 |
Follow rt-PA: new trials by email Literature Review of rt-PA trials Research Report on rt-PA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial rt-PA, DAPT - Lacunar Stroke, Stroke | Phase 4 | Recruiting | Nippon Medical School | 500 | 2025-08-01 | 2026-08-04 |
| Argatroban Plus R-tPA for Acute Ischemic Stroke rt-PA, Argatroban - Stroke | Phase 4 | Completed | General Hospital of Shenyang Military Region | 808 | 2018-12-21 | 2022-02-22 |
| Argatroban Plus r-tPA for Posterior Circulation Infarction（AR-PCI） Argatroban combined with rt-PA, rt-PA - Argatroban, Rt-PA | Phase 4 | Terminated | Hui-Sheng Chen | 3 | 2018-07-11 | 2018-11-14 |
| The Efficacy and Safety of rhTNK-tPA in Comparison With Alteplase(Rt-PA) as Fibrinolytic Therapy of Acute STEMI rhTNK-tPA, alteplase - Acute ST Elevation Myocardial Infarction | Phase 4 | Completed | CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd. | 818 | 2016-05-01 | 2022-05-25 |
| EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction Alteplase, Early post-fibrinolytic catheterisation, Primary PCI - Acute ST-segment Elevation Myocardial Infarction | Phase 4 | Completed | RenJi Hospital | 344 | 2014-01-13 | 2017-08-29 |
| Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA rt-PA (2mg/2mL) actilysis, rt-PA - Malfunction; Catheter, Thrombosis | Phase 4 | Unknown | Centre Hospitalier du Centre du Valais | 240 | 2011-01-01 | 2012-08-22 |
| Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD Recombinant tissue plasminogen activator (rt-PA), Low Molecular Weight Heparin - Pulmonary Thromboembolisms, Pulmonary Embolism | Phase 4 | Unknown | Beijing Chao Yang Hospital | 460 | 2009-07-01 | 2012-02-14 |
| Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China rt-PA - Pulmonary Embolism, Thromboembolism | Phase 4 | Completed | Beijing Chao Yang Hospital | 118 | 2002-06-01 | 2008-10-29 |
Pulmonary Embolism (2) · Stroke (2) · Ischemic Stroke (1) · Myocardial Infarction (1) · ST Elevation Myocardial Infarction (1) · Stroke, Lacunar (1) · Thromboembolism (1) · Thrombosis (1) · Ventricular Dysfunction, Right (1)
Beijing Chao Yang Hospital (2) · CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd. (1) · Centre Hospitalier du Centre du Valais (1) · General Hospital of Shenyang Military Region (1) · Hui-Sheng Chen (1) · Nippon Medical School (1) · RenJi Hospital (1)
China (6) · Japan (1) · Switzerland (1)
Ben He, MD (1) · Chen Wang, PhD,MD (1) · Huisheng Chen, Doctor (1) · Pascal Meier, MD (1) · Qin Yang, MD (1) · Shubin Qiaos, MD (1) · Yuki Sakamoto (1)
PMID 19741062, PMID 20667989, PMID 28844990, PMID 28928186, PMID 32485328, PMID 36757755, PMID 37265385, PMID 40635702, PMID 41678142