6 completed, 1 recruiting. 3 Phase 2, 2 Phase 1, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow rhTSH: new trials by email Literature Review of rhTSH trials Research Report on rhTSH
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC Selpercatinib, Sodium Iodine I-131, rhTSH - Thyroid Cancer, Thyroid Carcinoma | Phase 2 | Recruiting | Massachusetts General Hospital | 30 | 2023-03-01 | 2024-12-12 |
| rhTSH for Radioactive Iodine Remnant Ablation in Participants With Differentiated Thyroid Cancer (DTC) rhTSH, Radioiodine (131I) - Differentiated Thyroid Cancer | Phase 3 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 390 | 2021-10-06 | 2026-09-08 |
| Comparison of the Efficacy and Safety of rhTSH as An Adjunctive Diagnostic Tool in Differentiated Thyroid Cancer Patients Who Had Been Thyroidectomized Vs. Patients Who After Thyroid Hormone Withdrawal rhTSH - Differentiated Thyroid Cancer | Phase 3 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 201 | 2021-09-10 | 2024-03-28 |
| Clinical Trial of Dose-tolerance, Pharmacokinetics and Iodine Uptake For rhTSH In Post-thyroidectomized Patients Recombinant Human Thyroid Stimulating Hormone for Injection - Differentiated Thyroid Cancer | Phase 1 / Phase 2 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 64 | 2019-06-10 | 2024-03-06 |
| Efficacy of MEK (Trametinib) and BRAFV600E (Dabrafenib) Inhibitors With Radioactive Iodine (RAI) for the Treatment of Refractory Metastatic Differentiated Thyroid Cancer Trametinib, Dabrafenib, 131I - Metastatic Radioactive Iodine Refractory Thyroid Cancer Patients With RAS or BRAF Mutation | Phase 2 | Completed | Gustave Roussy, Cancer Campus, Grand Paris | 40 | 2017-12-27 | 2026-03-23 |
| Evaluation of Thyroid Stunning From a Diagnostic Dose of I-123 rhTSH - Differentiated Thyroid Cancer | Phase 1 | Completed | University of Colorado, Denver | 5 | 2012-11-30 | 2019-10-24 |
| Quality of Life, Recombinant TSH (Thyrogen) and Thyroid Cancer rhTSH - Thyroid Cancer | Phase 4 | Completed | Copenhagen University Hospital at Herlev | 56 | 2008-02-01 | 2013-01-10 |
Thyroid Neoplasms (3) · Adenocarcinoma, Follicular (1) · Thyroid Cancer, Papillary (1)
Suzhou Zelgen Biopharmaceuticals Co.,Ltd (3) · Copenhagen University Hospital at Herlev (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Massachusetts General Hospital (1) · University of Colorado, Denver (1)
China (3) · United States (2) · Denmark (1) · France (1)
Yansong Lin, PhD (2) · Birte Nygaard, Md, PhD (1) · Jennifer Kwak, MD (1) · Lori J. Wirth, MD (1) · Yansong Lin, MD (1)
PMID 37350119, PMID 40488858, PMID 41861727
2017 (1)