3 completed, 1 recruiting. 2 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Recruiting 1 |
Follow Pirfenidone (PFD): new trials by email Literature Review of Pirfenidone (PFD) trials Research Report on Pirfenidone (PFD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF) Deupirfenidone, Pirfenidone (PFD) - Idiopathic Pulmonary Fibrosis (IPF) | Phase 3 | Recruiting | PureTech | 1100 | 2026-06-26 | 2026-10-23 |
| Fibrosis-Modulating Effects of Metformin and Pirfenidone in Oral Submucous Fibrosis Metformin Hydrochloride 500Mg Tablet, Pirfenidone (PFD), Beclomaethasone and Vitamin E - Oral Submucous Fibrosis | Phase 1 / Phase 2 | Completed | Ziauddin University | 45 | 2025-04-07 | 2026-02-03 |
| PK of Deupirfenidone Versus Pirfenidone in Older Healthy Subjects Deupirfenidone, Pirfenidone (PFD), Placebo - Pharmacokinetic Analysis | Phase 1 | Completed | PureTech | 116 | 2021-07-12 | 2026-03-06 |
| Scleroderma Lung Study III - Combining Pirfenidone With Mycophenolate Pirfenidone (PFD), Placebo (Plac), Mycophenolate Mofetil (MMF) - Scleroderma, Systemic, Interstitial Lung Disease | Phase 2 | Completed | Michael Roth | 51 | 2017-11-28 | 2023-12-15 |
Idiopathic Pulmonary Fibrosis (1) · Lung Diseases (1) · Lung Diseases, Interstitial (1) · Oral Submucous Fibrosis (1) · Pulmonary Fibrosis (1) · Scleroderma, Systemic (1)
PureTech (2) · Michael Roth (1) · Ziauddin University (1)
United States (3) · Canada (1) · Pakistan (1)
Bruce G Rankin, DO (1) · Michael A Hassman, DO (1) · Michael D Roth, MD (1) · Steven H Reynolds, DO (1)
2025 (1)