4 completed, 2 unknown. 6 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Unknown 2 |
Follow Pilocarpine: new trials by email Literature Review of Pilocarpine trials Research Report on Pilocarpine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms Pilocarpine, brimonidine, oxymetazoline, hyaluronic acid, bromfenac (PBOHB) compound - Presbyopia | Phase 1 | Unknown | Optall Vision | 11 | 2021-08-14 | 2021-08-17 |
| Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients Compound Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac, Pilocarpine Hydrochloride, Brimonidine Tartrate - Presbyopia | Phase 1 | Unknown | Optall Vision | 11 | 2021-08-10 | 2021-08-19 |
| Compound to Control Presbyopia Symptoms PBO to control presbyopia symptoms - Presbyopia | Phase 1 | Completed | Optall Vision | 11 | 2020-06-01 | 2021-08-19 |
| First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology ASP6282, Itraconazole, Pilocarpine - Healthy Volunteers | Phase 1 | Completed | Astellas Pharma Europe B.V. | 116 | 2015-05-01 | 2016-07-01 |
| A Study to Investigate the Effect of Oral Doses of Pilocarpine on Salivary Secretion and Static Pupillometry in Healthy Subjects Pilocarpine, Placebo - Healthy Subjects | Phase 1 | Completed | Astellas Pharma Europe B.V. | 12 | 2015-05-01 | 2015-08-13 |
| Effects of Novel Combinations of Tolterodine/Pilocarpine on Pharmacokinetics (PK) and Pharmacodynamics (PD) of Tolterodine in Healthy Subjects Tolterodine, Pilocarpine, THVD-201 - Incontinence | Phase 1 | Completed | TheraVida, Inc. | 18 | 2009-09-01 | 2015-12-30 |
Presbyopia (3)
Optall Vision (3) · Astellas Pharma Europe B.V. (2) · TheraVida, Inc. (1)
Mexico (3) · United Kingdom (2) · Germany (1)
Cesar Alejandro S Galeana, MD (2) · Cesar Alejandro S Galeana (1) · Joanne Marjason (1)
2014 (1), 2015 (1)