4 completed, 1 terminated. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
Follow PHY 906: new trials by email Literature Review of PHY 906 trials Research Report on PHY 906
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC) Sorafenib+YIV-906, Sorafenib+placebo - Advanced Hepatocellular Carcinoma | Phase 2 | Completed | Yiviva Inc. | 62 | 2020-01-10 | 2025-04-13 |
| Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer Chinese herbal formulation PHY906, sorafenib tosylate, laboratory biomarker analysis - Adult Primary Hepatocellular Carcinoma, Advanced Adult Primary Liver Cancer | Phase 1 | Completed | City of Hope Medical Center | 18 | 2014-06-11 | 2021-01-27 |
| A Phase I/II, Multi-Center, Open-Label, Dose-Escalation, Safety and Efficacy Study of PHY906 Plus Capecitabine in Patients With Advanced Pancreatic Carcinoma Capecitabine, PHY906 - Pancreatic Cancer | Phase 1 / Phase 2 | Completed | Yale University | 25 | 2006-12-01 | 2015-03-27 |
| Study of Botanical PHY906 Plus Capecitabine for Advanced Unresectable Hepatocellular Carcinoma PHY906, capecitabine - Hepatocellular Carcinoma, Liver Cancer | Phase 1 / Phase 2 | Completed | PhytoCeutica | 31 | 2003-10-01 | 2007-03-28 |
| Safety Study of the Chemotherapy Modulator PHY906 in Patients With Advanced Colorectal Cancer PHY906 - Colorectal Neoplasms, Diarrhea | Phase 1 / Phase 2 | Terminated | PhytoCeutica | 30 | 2002-02-01 | 2005-06-24 |
Carcinoma, Hepatocellular (3) · Colorectal Neoplasms (1) · Diarrhea (1) · Hepatitis B (1) · Liver Neoplasms (1) · Pancreatic Neoplasms (1)
PhytoCeutica (2) · City of Hope Medical Center (1) · Yale University (1) · Yiviva Inc. (1)
United States (5) · Taiwan (2) · China (1) · Hong Kong (1)
Ghassan Abou-Alfa, MD/MBA (1) · Howard Hochester, MD (1) · Joseph Chao, MD (1) · Wayne D Brenckman, Jr., MD (1) · Yun Yen, MD/PhD (1)
PMID 12620148, PMID 19846955, PMID 20092990, PMID 21859559, PMID 24297682
P01CA154295 (1)