9 completed, 2 withdrawn, 1 active not recruiting, 1 recruiting. 8 Not applicable, 3 Phase 1, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Active not recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 2, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Phosphatidylcholines: new trials by email Literature Review of Phosphatidylcholines trials Research Report on Phosphatidylcholines
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development Placebo, Choline - Child Development, Cannabis Use | Phase 1 | Recruiting | University of Colorado, Denver | 140 | 2024-11-25 | 2025-02-03 |
| Efficacy of Diet on Quality of Life in Multiple Sclerosis BodyBio Balance Oil, Kirunal Fish Oil, BodyBio PC - Multiple Sclerosis, Relapsing-Remitting | Not applicable | Active not recruiting | Terry L. Wahls | 162 | 2022-02-10 | 2026-09-18 |
| Impact Of Choline in Patients With NAFLD Phosphatidyl Choline - Non-Alcoholic Fatty Liver Disease | Not applicable | Unknown | Ain Shams University | 100 | 2022-02-01 | 2022-10-18 |
| Choline Supplementation During Pregnancy: Impact on Attention and Social Withdrawal Choline, Placebo - Child Development, Prenatal Stress | Phase 1 | Completed | University of Colorado, Denver | 216 | 2017-06-12 | 2026-01-07 |
| Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans Choline Bitartrate, Pre-cooked, pre-peeled whole hardboiled eggs, Egg whites from pre-cooked, pre-peeled hardboiled eggs - Cardiovascular Risk Factor | Not applicable | Completed | The Cleveland Clinic | 86 | 2016-09-02 | 2026-07-13 |
| Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis Paeoniflorin + phosphatidylcholine or silymarin, Phosphatidylcholine or silymarin - Hepatitis, Autoimmune | Phase 3 | Withdrawn | Xiaoli Fan | 2016-08-01 | 2017-07-13 | |
| Efficacy of Phosphatidylcholine in NAFLD Phosphatidyl Choline, Lifestyle modification - Non-Alcoholic Fatty Liver Disease | Phase 3 | Completed | Nehal Abou Seada | 100 | 2016-01-02 | 2020-06-04 |
| Essentiale® Paste in Patients With Gastrointestinal Symptoms in Acute or Chronic Liver Diseases Phosphatidylcholine - Hepatic and Hepatobiliary Disorders | Phase 3 | Completed | Sanofi | 147 | 2015-08-01 | 2016-07-04 |
| Dietary Supplementation to Increase Serum Choline Levels Phosphatidylcholine, Betaine (588 mg qam and 412 mg qpm), Betaine (1000 mg BID) - Healthy | Not applicable | Completed | University of Colorado, Denver | 8 | 2015-04-01 | 2020-09-02 |
| Phosphatidylcholine Supplementation in Infants phosphatidylcholine supplementation, placebo - Schizophrenia, Diminished P50 Sensory Gating | Phase 1 / Phase 2 | Withdrawn | University of Colorado, Denver | 2013-09-01 | 2020-09-02 | |
| Study to Evaluate the Effect of Injection Lypolysis (Lipodissolve) Treatments to Reduce Body Fat phosphatidylcholine and deoxycholate - Abdominal Subcutaneous Fat | Not applicable | Completed | BodyAesthetic Research Center | 20 | 2008-06-01 | 2013-02-07 |
| Supplemental Choline and Brain Development in Humans Phosphatidylcholine, Corn oil placebo - Healthy | Not applicable | Completed | The Gerber Foundation | 150 | 2004-12-01 | 2010-06-22 |
| Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers supplementation with phosphatidylcholine - Healthy, Cardiovascular Diseases | Not applicable | Completed | Wageningen Centre for Food Sciences | 26 | 2003-05-01 | 2005-06-24 |
| Study of Phosphatidylcholine in a Patient With Methionine Adenosyltransferase Deficiency phosphatidylcholine - Methionine Adenosyltransferase Deficiency, Metabolism, Inborn Errors | Not applicable | Completed | National Center for Research Resources (NCRR) | 1 | 2000-01-01 | 2005-06-24 |
Non-alcoholic Fatty Liver Disease (2) · Cardiovascular Diseases (1) · Digestive System Diseases (1) · Fatigue (1) · Genetic Diseases, Inborn (1) · Hepatitis, Autoimmune (1) · Hypermethioninemia (1) · Metabolism, Inborn Errors (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Rare Diseases (1) · Schizophrenia (1)
University of Colorado, Denver (4) · Ain Shams University (1) · BodyAesthetic Research Center (1) · National Center for Research Resources (NCRR) (1) · Nehal Abou Seada (1) · Sanofi (1) · Terry L. Wahls (1) · The Cleveland Clinic (1) · The Gerber Foundation (1) · Wageningen Centre for Food Sciences (1) · Xiaoli Fan (1)
United States (8) · China (1) · Egypt (1) · Netherlands (1) · Russia (1)
Camille Hoffman, MD (2) · Ann Olincy, MD (1) · Doaa Zakaria, PhD (1) · Elizabeth J Brink, PhD (1) · Lamia El Wakeel, PhD (1) · Li Yang, MD (1) · M. Camille Hoffman, MD (1) · Petra Verhoef, PhD (1) · Randal G Ross, MD (1) · Robert Freedman, MD (1) · Sharon Hunter, PhD (1) · Steven H. Zeisel (1) · Terry L Wahls, MD (1) · V. Leroy Young, M.D. (1)
PMID 20534746, PMID 23134891, PMID 23439063, PMID 24476345, PMID 27217791, PMID 28394724, PMID 28714183, PMID 29866196, PMID 30050374, PMID 30736445, PMID 30832289, PMID 30871265, PMID 32213121, PMID 32575774, PMID 33872583, PMID 40838115, PMID 41146285
UL1TR001082 (1)