3 unknown, 2 recruiting, 2 terminated, 1 active not recruiting. 6 Phase 2, 5 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Recruiting 2, Unknown 2, Active not recruiting 1, Completed 1 |
| Phase 1 | 5 | Terminated 2, Unknown 2, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of LM-108 ± Penpulimab+Chemotherapy in Advanced Solid Tumors - Cohort C LM-108 injection, Penpulimab injection, Paclitaxel for injection (albumin bound) - Advanced Pancreatic Cancer | Phase 1 / Phase 2 | Recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 72 | 2025-04-11 | 2026-03-10 |
| Clinical Study of TQB2223 Injection Combined With AK105 Injection in the Treatment of Advanced Hepatocellular Carcinoma. TQB2223 injection, Penpulimab Injection - Advanced Hepatocellular Carcinoma | Phase 1 | Terminated | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 22 | 2024-05-30 | 2025-11-21 |
| A Clinical Study of TQB2618 Injection Monotherapy and Combination Regimen (With Penpulimab Injection ±Anlotinib Hydrochloride Capsules) in the Four or Later Lines of Treatment of Advanced Colorectal Cancer. TQB2618 injection, Penpulimab injection, Anlotinib hydrochloride capsules - Colorectal Cancer | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 75 | 2024-01-13 | 2024-01-23 |
| Penpulimab Combined With Chemotherapy for Neoadjuvant and Adjuvant Therapy in Patients With Resectable HNSCC Penpulimab injection, cisplatin, albumin-paclitaxel - Head and Neck Squamous Cell Carcinoma | Phase 2 | Active not recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 72 | 2023-10-17 | 2026-09-30 |
| A Clinical Study of TQB2618 Injection Combined With Penpulimab Injection and Anlotinib Hydrochloride Capsules for First-line Treatment of Advanced Hepatocellular Carcinoma (HCC). Penpulimab injection, TQB2618 injection, Anlotinib Hydrochloride Capsules - Advanced Hepatocellular Carcinoma | Phase 1 | Terminated | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 29 | 2023-08-15 | 2025-08-12 |
| To Evaluate the Safety and Efficacy of TQB2618 Injection Combined With Penpulimab in the Treatment of Patients With Relapsed and Refractory Lymphoma TQB2618 injection, Penpulimab injection - Relapsed/Refractory Lymphoma | Phase 1 / Phase 2 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 92 | 2022-06-09 | 2023-02-14 |
| XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma Anlotinib hydrochloride capsule, Penpulimab Injection, XELOX - Carcinoma, Gastrointestinal Diseases | Phase 2 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 80 | 2022-03-16 | 2023-11-07 |
| Study of AK105 With Anlotinib and Radiotherapy Adjuvant Therapy in MGMT Unmethylated Newly Diagnosed Glioblastoma. Anlotinib, AK105, Radiotherapy - MGMT-Unmethylated Glioblastoma | Phase 2 | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 28 | 2021-09-01 | 2021-09-05 |
| Gut Microbial Metabolites Inosine Combined With PD-1/PD-L1 Inhibitor for Patients With Malignant Advanced Solid Tumors Inosine 0.2g orally 3 times/day, PD-1/PD-L1 inhibitor ,chemotherapy/targeting - Advanced Solid Tumor | Phase 2 / Phase 3 | Completed | Beijing Friendship Hospital | 172 | 2019-05-01 | 2023-04-12 |
Carcinoma (1) · Colorectal Neoplasms (1) · Digestive System Diseases (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Lymphoma (1) · Squamous Cell Carcinoma of Head and Neck (1) · Stomach Neoplasms (1)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (5) · Beijing Friendship Hospital (1) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (1) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (1) · The First Affiliated Hospital with Nanjing Medical University (1)
China (9)