2 active not recruiting, 1 completed, 1 withdrawn. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 2, Completed 1, Withdrawn 1 |
| Phase 1 | 2 | Active not recruiting 1, Completed 1 |
Follow PDS0101: new trials by email Literature Review of PDS0101 trials Research Report on PDS0101
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CASCADE: Testing for Safety and Immune Effects of PDS0101, an Anti-HPV Therapy, Among People Living With HIV PDS0101 - HPV Associated Cancers, HIV (Human Immunodeficiency Virus) | Phase 2 | Withdrawn | University of California, San Diego | 2026-04-30 | 2026-08-19 | |
| A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101, Pembrolizumab, Computed Tomography - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Human Papillomavirus-Related Carcinoma | Phase 1 / Phase 2 | Active not recruiting | Mayo Clinic | 20 | 2022-06-16 | 2026-10-07 |
| A Vaccine (PDS0101) and Chemoradiation for the Treatment of Stage IB3-IVA Cervical Cancer, the IMMUNOCERV Trial Cisplatin, Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101, Radiation Therapy - Locally Advanced Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Stage IB3 Cervical Cancer FIGO 2018 | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 22 | 2020-10-14 | 2026-04-15 |
| Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies PDS0101, M7824, NHS-IL12 - Cervical Cancer, HPV Cancers | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 51 | 2020-06-09 | 2026-06-30 |
Anus Neoplasms (2) · Oropharyngeal Neoplasms (2) · Uterine Cervical Neoplasms (2) · Acquired Immunodeficiency Syndrome (1) · Carcinoma (1) · Rectal Neoplasms (1)
M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · University of California, San Diego (1)
United States (4) · Puerto Rico (1)
Ann H Klopp (1) · Charalampos Floudas, M.D. (1) · David M. Routman, M.D. (1) · Timothy Wilkin, MD, MPH (1)
U24CA275417 (1), UG1CA275414 (1), UG1CA284883 (1), UG1CA284884 (1)