6 completed, 4 active not recruiting, 3 recruiting, 3 unknown. 7 Phase 3, 6 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 5, Terminated 1, Unknown 1 |
| Not applicable | 6 | Active not recruiting 2, Recruiting 2, Suspended 1, Withdrawn 1 |
Follow Ovariectomy: new trials by email Literature Review of Ovariectomy trials Research Report on Ovariectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HYbrid RObotic Surgery in Gynecology Hysterectomy or Hysterectomy with Bilateral Salpingectomy or Hysterectomy with bilateral Salpingectomy and Oophorectomy - Hysterectomy, Hysterectomy and Salpingectomy | Not applicable | Recruiting | Rob Surgical Systems S.L. | 9 | 2026-10-01 | 2026-09-22 |
| Hormonal Regulation of Cardiometabolic Health Study Surgical removal of ovaries, Hormone Replacement Therapy (HRT) - Menopause Surgical | Recruiting | University of Jyvaskyla | 120 | 2026-02-13 | 2026-05-06 | |
| Comparative Evaluation of Efficacy and Safety of Toremifene, Tamoxifen, and Aromatase Inhibitor Plus Ovarian Function Suppression in Hormone Receptor-Positive Early Breast Cancer Among Non-Low-Risk Premenopausal Women: A Real-World Study Aromatase inhibitor, ovarian function suppression (Oophorectomy, Ovarian irradiation, Gonadotropin-releasing hormone agonist), Tamoxifen - Hormone-receptor-positive Breast Cancer, Premenopausal Breast Cancer | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 700 | 2023-06-01 | 2023-05-18 | |
| A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection - Ovarian Carcinoma | Not applicable | Recruiting | NRG Oncology | 1956 | 2020-09-01 | 2026-08-07 |
| Ovarian Tissue Cryopreservation in the Setting of Gender-affirming Therapy Oophorectomy, Infectious Disease Testing - Gender Dysphoria, Transgender | Active not recruiting | University of Pittsburgh | 20 | 2020-07-14 | 2026-07-09 | |
| Expression Analysis of the COPB 2 and Bcl-2 in Early Stages of Endometrial Carcinoma 1.hysterectomy with bilateral oophorectomy and pelvic lymphonodectomy. 2 explorative curettage - Endometrial Carcinoma Cellular Diagnosis | Completed | Clinical Center Kragujevac | 60 | 2019-04-17 | 2023-07-19 | |
| Ovarian Tissue Cryopreservation for Fertility Preservation in Girls and Women Oophorectomy - Fertility Preservation | Not applicable | Suspended | Baylor College of Medicine | 24 | 2017-08-11 | 2023-06-18 |
| Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations Laboratory Biomarker Analysis, Oophorectomy, Quality-of-Life Assessment - Deleterious BARD1 Gene Mutation, Deleterious BRCA1 Gene Mutation | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 374 | 2016-05-02 | 2026-07-15 |
| The Association Between Ovarian Endometrioma and Lower Urinary Tract Symptoms Laparoscopic oophorocystectomy or oophorectomy - Ovarian Endometrioma | Unknown | Far Eastern Memorial Hospital | 90 | 2015-11-15 | 2022-02-08 | |
| Prediction of Recurrence Among Low Risk Endometrial Cancer Patients Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection, Hysterectomy - FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma | Active not recruiting | M.D. Anderson Cancer Center | 518 | 2012-11-08 | 2026-09-16 | |
| Cryopreservation of Ovarian Cortex in Girls With Turner Syndrome Ovariectomy - Turner Syndrome, Ovarian Insufficiency | Not applicable | Active not recruiting | Assistance Publique - Hôpitaux de Paris | 47 | 2011-01-01 | 2026-03-30 |
| Luteal vs Follicular Surgical Oophorectomy and Tamoxifen in Premenopausal Women With Metastatic Hormone Receptor Positive Breast Cancer oophorectomy, Tamoxifen - Breast Cancer | Phase 3 | Completed | International Breast Cancer Research Foundation | 249 | 2006-02-01 | 2016-07-27 |
| Adjuvant Oophorectomy and Tamoxifen in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Tamoxifen, Surgery: Oophorectomy - Breast Cancer | Phase 3 | Completed | International Breast Cancer Research Foundation | 740 | 2004-01-01 | 2015-04-29 |
| Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer Exemestane, Laboratory Biomarker Analysis, Oophorectomy - Estrogen Receptor Positive Breast Cancer, Progesterone Receptor Positive Tumor | Phase 3 | Completed | ETOP IBCSG Partners Foundation | 3066 | 2003-12-17 | 2026-08-26 |
| Premenopausal Endocrine Responsive Chemotherapy Trial chemotherapy, exemestane, tamoxifen - Breast Cancer | Phase 3 | Terminated | ETOP IBCSG Partners Foundation | 29 | 2003-08-01 | 2016-10-28 |
| Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who Are Undergoing Prophylactic Oophorectomy celecoxib, oophorectomy - brca1 Mutation Carrier, brca2 Mutation Carrier | Not applicable | Withdrawn | University of Alabama at Birmingham | 2002-06-01 | 2013-08-22 | |
| Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer | Phase 3 | Completed | Institute of Cancer Research, United Kingdom | 6000 | 1993-06-01 | 2013-08-02 |
| Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer cyclophosphamide, fluorouracil, goserelin acetate - Breast Cancer | Phase 3 | Completed | Scottish Cancer Therapy Network | 1000 | 1993-06-01 | 2013-11-06 |
| Adjuvant Hormone Therapy in Treating Women With Operable Breast Cancer goserelin acetate, tamoxifen citrate, ablative endocrine surgery - Breast Cancer | Phase 3 | Unknown | Cancer Research UK | 1987-09-01 | 2013-08-07 |
Breast Neoplasms (7) · Infertility (2) · Ovarian Neoplasms (2) · Carcinoma, Ovarian Epithelial (1) · Endometriosis (1) · Gender Dysphoria (1) · Health Behavior (1) · Hereditary Breast and Ovarian Cancer Syndrome (1) · Lower Urinary Tract Symptoms (1) · Neoplasm Metastasis (1) · Sexual Dysfunction, Physiological (1) · Turner Syndrome (1)
ETOP IBCSG Partners Foundation (2) · International Breast Cancer Research Foundation (2) · M.D. Anderson Cancer Center (2) · Assistance Publique - Hôpitaux de Paris (1) · Baylor College of Medicine (1) · Cancer Research UK (1) · Clinical Center Kragujevac (1) · Far Eastern Memorial Hospital (1) · Institute of Cancer Research, United Kingdom (1) · NRG Oncology (1) · Rob Surgical Systems S.L. (1) · Scottish Cancer Therapy Network (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1) · University of Alabama at Birmingham (1) · University of Jyvaskyla (1)
United States (8) · United Kingdom (3) · Canada (2) · China (2) · Morocco (2) · Philippines (2) · Switzerland (2) · Vietnam (2) · Bangladesh (1) · Belgium (1) · Finland (1) · France (1) · Hungary (1) · India (1) · Indonesia (1)
Chang Gong, docto (1) · Edith A. Perez, MD (1) · Edward E. Partridge, MD (1) · Eija K Laakkonen, Associate Professor (1) · Gini Fleming (1) · Helena Earl, MBBS, PhD, FRCP (1) · John R. Yarnold, MD, FRCR (1) · Kathryn P Pennington (1) · Kyle Orwig, PhD (1) · Lise Duranteau, MD, PhD (1) · Michael Baum, MD, ChM, FRCS (1) · Richard R. Love, M.D. (1) · Richard R. Love, MD (1) · Roni N Wilke, MD (1)
PMID 10663329, PMID 17405995, PMID 17405996, PMID 24095609, PMID 24881463, PMID 25495490, PMID 26092816, PMID 27022111, PMID 27044936, PMID 27107325, PMID 28911092, PMID 29863451, PMID 31443726, PMID 31618131, PMID 36493334, PMID 36521078, PMID 39509704, PMID 40986647, PMID 41637791, PMID 42412428
2004 (1), 2005 (1), U24CA075362 (1), UG1CA189867 (1)